NSAID-gastropathy in patients with cardiac disease
https://doi.org/10.25789/YMJ.2018.63.10
Abstract
The character of clinical endoscopic features of gastropathies, induced by the intake of non-steroidal anti-inflammatory drugs, was evaluated in patients with cardiac pathology.
The clinical picture of NSAIDs-gastropathies in patients with IHD was characterized by a mismatch of symptoms and endoscopic changes. This manifested itself in the fact that in the presence of a bright endoscopic picture (erosion, ulcer), NSAIDs-gastropathies were often asymptomatic. In contrast, in most patients who have noticed pain or other dyspeptic disorders, endoscopic examination revealed minimal changes in the mucosa of the gastroduodenal zone. Therefore, carrying out endoscopic control, preferably in the early stages of treatment, is the most necessary and mandatory method of preventing serious complications.
About the Authors
L. A. Lytkina
Medical Institute of the M.K. Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
Chibyeva Lyudmila Grigoryevna - Doctor of Medical Sciences, professor of the department of propaedeutics and faculty therapy with endocrinology and exercise therapy
Yakutsk
L. G. Chibyeva
Medical Institute of the M.K. Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
Lytkina Alina Albertovna - post-graduate student of the department of propaedeutic and faculty therapy with endocrinology and exercise therapy
Yakutsk
References
1. Alekseenko SA. The modern approaches to prophylaxis of nonsteroidal antiinflammatory -gastropathies / S.A. Alekseenko, M.A. Sivak// DMJ.-2015. - №2 – P. 123-128.
2. Safety and pharmacoeconomic effectiveness of use of various medicines of Acidum acetylsalicylicum for patients with an ischemic heart disease / A.L. Vyortkin, O.Ya. Aristarkhova, E.V. Adonina [et al.] //RMJ. - 2009. - №8. – P.15-19.
3. Zvenigorodskaya L.A. New opportunities of a gastroprotection at patients with an ischemic heart disease against the background of reception of anti-aggregant therapy by small doses of Aspirin /L. A. Zvenigorodskaya, E.Y. Bondarenko//Heart. – 2008. – V.7. - №2. – р.118-120.
4. Morozova T.E. NSAIDs-gastropathies at patients with the combined pathology of cardiac vascular system and diseases of joints and a backbone / T.E. Morozova, S.M. Rykova, M.A. Chukina // Experimental and clinical gastroenterology. - №6. – 2015. – P. 64-70.
5. Karateev A.E. Problem NSAIDs-gastropathies: the modern representations / A.E. Karateev, E.V. Moroz //Medical alphabet. – 2017. – V.4. - №40. – P. 13-20.
6. Shavlovskaya O.A. Advantages of NSAIDs, selective inhibitors of cyclooxigenase-2 in therapy of a pain syndrome / O.A. Shalovskaya // Reference book of the polyclinic doctor. – 2014. – №3. – P. 46-49.
7. Harirforoosh S. Adverse Effects of Nonsteroidal Antiinflammatory Drugs: An Update of Gastrointestinal, Cardiovascular and Renal Complications / S. Harirforoosh, W. Asghar, F. Jamali // J Pharm Pharm Sci. – 2013. – №16 (5). – р.821-847.
Review
For citations:
Lytkina L.A., Chibyeva L.G. NSAID-gastropathy in patients with cardiac disease. Yakut Medical Journal. 2018;(3):35-36. https://doi.org/10.25789/YMJ.2018.63.10
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