Genetic diversity in Yakut population by loci associated with body mass index and obesity
https://doi.org/10.25789/YMJ.2019.67.06
Abstract
In the present study the variability of the GWAS-identified SNP allele frequencies associated with BMI and obesity was studied. The results of our study were compared with data on 20 populations from the international project “1000 Genomes”. Genetic markers that make the greatest contribution to the genetic differentiation of populations were identified.
Supporting agencies: This work was carried out with the support of the Russian Foundation for Basic Research No. 18-04-00758.
About the Authors
A. A. Popovich
Research Institute of Medical Genetics, Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center of the Russian Academy of Sciences»
Russian Federation
Russian Federation
Popovich Anastasia Andreevna, Ph.D. Junior Researcher
E. A. Trifonova
Research Institute of Medical Genetics, Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center of the Russian Academy of Sciences»
Russian Federation
Russian Federation
Trifonova Ekaterina Aleksandrovna, Ph.D. Scientific Researcher
A. V. Bocharova
Research Institute of Medical Genetics, Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center of the Russian Academy of Sciences»
Russian Federation
Russian Federation
Bocharova Anna Vladimirovna Junior Researcher
K. V. Vagaitseva
Research Institute of Medical Genetics, Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center of the Russian Academy of Sciences»
Russian Federation
Russian Federation
Vagaitseva Ksenia Valerievna, Ph.D. Scientific Researcher
N. R. Maximova
Medical Institute of Federal state Autonomous educational institution of higher professional education «North-Eastern Federal University named after M. K. Ammosov»
Russian Federation
Russian Federation
Maximova Nadezhda Romanovna, Dr.Sc. Chief Researcher of the Clinic
V. A. Stepanov
Research Institute of Medical Genetics, Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center of the Russian Academy of Sciences»;
Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center of the Russian Academy of Sciences»
Russian Federation
Russian Federation
Stepanov Vadim Anatolevich, Dr.Sc., correspondent member RAS Head of the Laboratory of Evolutionary Genetics;
Acting Director
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Review
For citations:
Popovich A.A., Trifonova E.A., Bocharova A.V., Vagaitseva K.V., Maximova N.R., Stepanov V.A. Genetic diversity in Yakut population by loci associated with body mass index and obesity. Yakut Medical Journal. 2019;(3):23-26. (In Russ.) https://doi.org/10.25789/YMJ.2019.67.06
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