Analysis of microcirculatory disorders in patients with lichen ruber planus of oral mucosa
https://doi.org/10.25789/YMJ.2019.65.15
Abstract
To study microcirculatory changes in patients with erosive ulcerous form of red flat lichen, a comparative analysis of the parameters of the microcirculatory link and amplitude-frequency spectrum was carried out. Microcirculation was studied with the help of laser Doppler flowmetry (LDF). It was revealed that at the inflammatory-destructive lesion of the oral mucosa, there are an increase in the parameters of microcirculation against the background of a decrease in the average fluctuation in perfusion and a decrease in the vasomotor activity of the vessels. The amplitudefrequency spectrum showed a decrease in the amplitude of low-frequency flaws and an increase in the amplitude of the pulse and respiratory waves. Having high sensitivity to changes in the microhemodynamic situation in the vascular bed, the use of LDF makes it possible to evaluate the state of functioning of control mechanisms and is a valid method of application in gerontostomatological practice.
About the Authors
Ya. A. Makedonova
FGBOU VO “Volgograd State Medical University”;
Volgograd Medical Scientific Center
Russian Federation
Russian Federation
Makedonova Julia Alekseevna - Candidate of Medical Sciences, Associate Professor of the Department of Therapeutic Dentistry;
senior researcher at the Laboratory of pathology modeling
Volgograd, 400105. St. M.Eremenko 98-9
89173332400
E. V. Fomichev
FGBOU VO “Volgograd State Medical University”
Russian Federation
Russian Federation
Fomichev Evgeniy Valentinovich - Doctor of Medical Sciences, Professor, Head of the Department of Surgical Dentistry and Maxillofacial Surgery
Volgograd, 400081, st. Angarskaya 7B – 44
89375541234
K. V. Zhmerenetskiy
FGBOU VO “Far East state medical University”
Russian Federation
Russian Federation
Zhmerenetskiy Konstantin Vyacheslavovich – rector
doctor of medical sciences, member of correspondent RAS
Khabarovsk, 680000, st. Muraveva-Amur 35-224
89145488703
A. V. Yurkevich
“Far East state medical university”
Russian Federation
Russian Federation
Yurkevich Alexander Vladimirovich - doctor of medical sciences, associate professor, head of Department of orthopedic stomatology
Khabarovsk, 680000, st. Muravieva-Amurskogo 35-233
89655025888
I. D. Ushnitsky
M. K. Ammosov NEFU Medical Institute
Russian Federation
Russian Federation
Ushnitsky Innokenty Dmitrievich - doctor of medical sciences, professor, head of the Department of therapeutic, surgical, orthopedic dentistry and pediatric dentistry
Yakutsk, 677000, st. Oyunsky 27-420
89241708940
References
1. Grigoryan A.A. Development and clinical use of new wound healing means for treatment of diseases of a mucous membrane of the oral cavity among children and teenagers / A.A. Grigoryan, S.V. Sirak, A.G. Sirak, S.A. Khanova// Modern problems of science and education. – 2013. – № 2. – P. 41. https://elibrary.ru/item.asp?id=21285392
2. The research of hemodynamics and functional condition of the vascular system of normal/pathological red border of lips (clinical aspects) / S.V. Sirak, E.V. Shchetinin, E.M. Kirzhinova [et al.] //Medical bulletin of the North Caucasus. 2015. – V.10, № 1(37). – P. 76-80. DOI: 10.14300/mnnc.2015.10012.
3. Clinical studying of dynamics of reparative processes of the mucous membrane of the oral cavity at platelet autoplasma use in complex treatment of patients with red flat herpes(es) / I.V. Firsova, Yu.A. Makedonova, N.Sh. Martynova [et al.] // Modern problems of science and education. – 2015. – № 5; URL: http://www.science-education.ru/128-22645.
4. Kozlov V.I. Metod of laser Doppler flowmetry: manual for doctors / V.I. Kozlov, E.S. Mach, F.B. Litvin // M., 2001. – 22 P. http://journals.rudn.ru/medicine/article/view/3260
5. The morphological analysis of periodontium condition when using different types of sealers in endodontics /I. V. Firsova, Yu.A. Makedonova, D.V. Mikhalchenko [et al.] //Medical bulletin of the North Caucasus. – 2015. – V.10, № 4. – P. 389-394. DOI: 10.14300/mnnc.2015.00095.
6. New approach to therapy of chronic recurrent aphthous stomatitis (setton aphthosis) with the use of method of photoactivated disinfection and immunomodulator of Galavit / V.F. Mikhalchenko, I.V. Firsova, Yu.M. Fedotova [et al.] // Modern problems of science and education. – 2015. – № 6. – P. 181. https://science-education.ru/ru/article/view?id=23489
7. Use of PRP therapy in treatment of inflammatory diseases of a mucous membrane of the oral cavity / N.Sh. Martynova, Yu.A. Makedonova, V.F. Mikhalchenko хуе фдюъ // Modern problems of science and education. – 2015. – № 5; URL: https://science-education.ru/ru/article/view?id=22439
8. The principle of quality and safety in modern dental practice / I.V. Firsova, S.V. Poroysky, Yu.A. Makedonova [et al.] // Modern problems of science and education. – 2014. – № 6; URL: http://www.science-education.ru/120-15530
9. Sabantseva E.G. Pathophysiological characteristic of disorders of microcirculation at inflammatory – destructive diseases of the mouth mucous membrane / E.G. Sabantseva // Regional blood circulation and microcirculation. – 2006. – №1. – P. 30-36. https://elibrary.ru/item.asp?id=11715561
10. Severina T.V. Change of capillary blood flow condition of a mucous membrane of the oral cavity at chronic recurrent aphthous stomatitis / T.V. Severina //Kuban scientific medical magazine. – № 1. – 2009. – P. 112-115. https://cyberleninka.ru/article/n/izmenenie-sostoyaniya-kapillyarnogokrovotoka-slizistoy-obolochki-polosti-rta-prihronicheskom-retsidiviruyuschem-aftoznomstomatite
11. Sirak S.V. Use of multicomponent adhesive ointment in combination with immunomodulatory drug in coMPLex therapy of pemphigus / S.V. Sirak, I.A. Kopylova, V.V. Chebotaryov, F.M.S. Al-asfari//Parodontologiya. – 2012. – V.17. – № 2. – P. 62-65. https://elibrary.ru/item.asp?id=17738462
12. Sirak S.V. Experience of use of local wound healing means at treatment of vulgar pemphigus with localization on the mucous membrane of the oral cavity and lips / S.V. Sirak, V.V. Chebotaryov, A.G. Sirak, A.A. Grigoryan //Medical bulletin of the North Caucasus. – 2013. – V. 8. – № 1. – P. 59-62. https://elibrary.ru/item.asp?id=18930212
13. Firsova I.V. Medical tactics at diagnostics of precancerous diseases of the mucous membrane of the oral cavity and red border of lips / I.V. Firsova, V.F. Mikhalchenko, D.V. Mikhalchenko //Messenger of the Volgograd state medical university. – 2013. – № 1 (45). – P. 3-6.https://elibrary.ru/item.asp?id=18944984
14. Yurkevich A.V. Pathomorphologic research of gingiva mucous membrane at stomach peptic ulcer / A.V. Yurkevich, D.V. Matsyupa, G.I. Oskolsky //Siberian Consultation. – 2005. – № 4. – P. 37-40. https://elibrary.ru/item.asp?id=28959556
15. Yurkevich A.V. Pathomorphologic analysis of gingiva mucous membrane at diabetes mellitus and stomach peptic ulcer: thesis for a degree of MD / A.V. Yurkevich //Research institute of regional pathology and patomorphology Russian Academy of Medical Science. -Novosibirsk, 2005. https://elibrary.ru/item.asp?id=32783602
16. Сlinical and experimental study of the regenerative features of oral mucosa under autohemotherapy / I.V. Firsova, Yu.A. Makedonova, D.V. Mikhalchenko [et al.] // Research Journal of Pharmaceutical, Biologicaland Chemical Sciences. – 2015. – Vol. 6, №6. – р. 1711-1716.https://elibrary.ru/item.asp?id=25012523
Review
For citations:
Makedonova Ya.A., Fomichev E.V., Zhmerenetskiy K.V., Yurkevich A.V., Ushnitsky I.D. Analysis of microcirculatory disorders in patients with lichen ruber planus of oral mucosa. Yakut Medical Journal. 2019;(1):48-51. https://doi.org/10.25789/YMJ.2019.65.15
Views:
1
Email this article 