Estimation of antiulcerous effect of multicomponent plant extract in experiment
https://doi.org/10.25789/YMJ.2019.65.14
Abstract
The authors report their study on the antiulcerous effect of a new multicomponent plant extract derived from the following species of medicinal plant materials: leaves of Plantago major L., grass of Gnaphalium uliginosum L., rhizomes and roots of a Inula helenium L., flowers of Matricaria chamomilla L., roots of Glycyrrhiza glabra L., grass of Polygonum aviculare L., grass of Urtica dioica L., fruits of Sorbus aucuparia L. in the ratio 3:3:3:2:2:1:1:1, in experiments on Wistar line rats. The findings of the research confirm the expressed antiulcerous effect of the plant extract which is comparable to the effects of befunginum and ranitidine. The coMPLex of biologically active substances contained in the extract promotes УдК 615;615.2435;616.33;616.34 DOI 10.25789/YMJ.2019.65.14 the acceleration of the ulcer healing due to its versatile influence on the main pathogenesis mechanisms of the given pathology.
About the Authors
E. V. Ferubko
All-Russian scientific research institute of Medicinal and Aromatic plants
Russian Federation
Russian Federation
Ferubko Ekaterina Vladimirovna – Ph. D. (Med.), Head of department of experimental and clinical pharmacology of the Center of Medicine
117216, Moscow, Grina Street, 7, Building 1
S. M. Nikolaev
General and Experimental Institute of Biology, Siberian branch of RAS
Russian Federation
Russian Federation
Nikolaev Sergey Matveevich – Dr. Sc. (Med.), prof., Chief researcher of Laboratory of experimental pharmacology
670046, Ulan-Ude, Sakh’yanovoy Street, 6
K. A. Pupykina
Federal state-funded educational institution of the higher education “The Bashkir state medical university” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Pupykina Kira Aleksandrovna - Dr. Sc. (Pharm.), prof. of department of a pharmacognosy with a course of botany and bases of a phytotherapy
450008, Ufa, Lenin Street, 3
T. D. Dargaeva
All-Russian scientific research Institute of Medicinal and Aromatic plants
Russian Federation
Russian Federation
Dargaeva Tamara Darizhapovna – Dr. Sc. (Pharm.), prof., Chief researcher of Department of standardization and certification
117216, Moscow, Grina Street, 7, Building 1
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Review
For citations:
Ferubko E.V., Nikolaev S.M., Pupykina K.A., Dargaeva T.D. Estimation of antiulcerous effect of multicomponent plant extract in experiment. Yakut Medical Journal. 2019;(1):45-47. https://doi.org/10.25789/YMJ.2019.65.14
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