Antioxidant activity of adaptogenic plant remedy in model systems in vitro
https://doi.org/10.25789/YMJ.2019.65.06
Abstract
The antioxidant activity of the dry extract from the complex plant remedy has been studied in model systems in vitro. It has been established that the plant remedy under study inhibits the oxidation of the biological substrate preventing from the destruction of β-carotene and yolk lipoproteids, making membrane stabilizing effect at peroxide and osmotic hemolysis of erythrocytes. The complex remedy manifests the radical binding activity for 2.2-diphenyl-1– picrylhydrazyl (DPPH˙), superoxide anion-radical, nitrogen oxide, also for Fe2+. The marked antioxidant activity of the tested remedy is due to the complex of biologically active substances (flavonoids, tannins, polyphenolic compounds, phenol carbonic acids, ecdysteroids, etc.) contained in its components.
Keywords
plant remedy,
adaptogens,
Serratula centauroides (L.),
Bergenia crassifоlia (L.) Fritsch,
Rosa davurica Pall.,
Inula helenium L.,
Echinacea purpurea (L.) Moench.,
membrane stabilizing activity,
2.2-diphenyl-1– picrylhydrazyl,
superoxide anion-radical,
nitrogen oxide
Supporting agencies: The studies were carried out in the course of the project N AAAA-A17-117011810037-0.
About the Authors
A. A. Toropova
Institute of General and Experimental Biology SB RAS
Russian Federation
Russian Federation
Toropova Anyuta Alekseevna - candidate of biological sciences, Research Scientist of the Laboratory of Biologically Active Substances Safety
670047, Ulan-Ude, Sakhyanova str., 6, ph. +7 (3012) 433713
B. A. Muruev
Institute of General and Experimental Biology, SB RAS
Russian Federation
Russian Federation
Muruev Bair Andreevich - Postgraduate student scientist of the Laboratory of Experimental Pharmacology
670047, Ulan-Ude, Sakhyanova str., 6; ph.: +7 (3012) 433713
Ya. G. Razuvaeva
Institute of General and Experimental Biology SB RAS
Russian Federation
Russian Federation
Razuvaeva Yanina Gennadyevna – doctor of biological sciences, Senior Research Scientist of the Laboratory of Biologically Active Substances Safety
670047, Ulan-Ude, Sakhyanova str., 6, ph. +7 (3012) 433713
I. G. Nikolaeva
Institute of General and Experimental Biology, Siberian Branch of the Russian Academy of Sciences
Russian Federation
Russian Federation
Nikolaeva Irina Gennadievna - doctor of Pharmacology, Senior Researcher of the Laboratory of Biomedical Research
670047, Ulan-Ude, ul. Sakhyanova, 6; tel .: +7 (3012) 433713
A. G. Mondodoev
Institute of General and Experimental Biology SB RAS
Russian Federation
Russian Federation
Mondodoev Alexander Gavrilovich - doctor of medical sciences, Head of the Department of Biologically Active Substances Safety
670047, Ulan-Ude, Sakhyanova str., 6, ph. +7 (3012) 433713
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Review
For citations:
Toropova A.A., Muruev B.A., Razuvaeva Ya.G., Nikolaeva I.G., Mondodoev A.G. Antioxidant activity of adaptogenic plant remedy in model systems in vitro. Yakut Medical Journal. 2019;(1):21-24. https://doi.org/10.25789/YMJ.2019.65.06
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