Brain pathology in schizophrenia: association with clinical and constitutional factors
E. G. Kornetova,
S. D. Koval’, 
A. N. Kornetov,
D. A. Parshukova,
S. A. Ivanova,
A. V. Semke,
S. V. Gusakova,
N. A. Bokhan
A. N. Kornetov,
D. A. Parshukova,
S. A. Ivanova,
A. V. Semke,
S. V. Gusakova,
N. A. Bokhan https://doi.org/10.25789/YMJ.2019.65.05
Abstract
The article reports the study of schizophrenia patients with the help of magnetic resonance imaging, anthropometry, PANSS psychometric evaluation, registering basic clinical signs with hereditary burden, duration of disorder and the main symptoms. The study shows that cysts and dyscirculatory foci are observed more often at negative disorders than at a positive domain. It may be connected with disontogenesis impact on severity of schizophrenia. There were also found the association between hyperstenic somatotype, increasing of big brain hemispheres subarachnoid areas and gynecomorphy with the expansion of the cerebellum subarachnoid space.
Keywords
Supporting agencies: The study was carried out with the financial support of grants: RSF18-15- 00053 “Search of peripheral markers associated with impaired myelination of the brain and pathogenesis of schizophrenia” in part of including of brain MRI examination with the results interpretation, and RSF18-15-00011 “Schizophrenia combined with metabolic syndrome: clinical-constitutional factors and molecular markers” in part of constitutionalmorphological examination with the data interpretation.
About the Authors
E. G. Kornetova
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
4 Aleutskaya street, 634014, Tomsk
+73822738775
S. D. Koval’
Siberian State Medical University
Russian Federation
Russian Federation
2 Moskovsky trakt, 634055, Tomsk
+73822901101-1738
A. N. Kornetov
Siberian State Medical University
Russian Federation
Russian Federation
2 Moskovsky trakt, 634055, Tomsk
+73822901101-1812
D. A. Parshukova
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
4 Aleutskaya street, 634014, Tomsk
+73822723832
S. A. Ivanova
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
4 Aleutskaya street, 634014, Tomsk
+73822723177
A. V. Semke
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences;
Siberian State Medical University
Russian Federation
Russian Federation
4 Aleutskaya street, 634014, Tomsk
+73822724379
2 Moskovsky trakt, 634055, Tomsk
S. V. Gusakova
Siberian State Medical University
Russian Federation
Russian Federation
2 Moskovsky trakt, 634055, Tomsk
+73822901101-1814
N. A. Bokhan
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences;
Siberian State Medical University
Russian Federation
Russian Federation
4 Aleutskaya street, 634014, Tomsk
+73822724015
2 Moskovsky trakt, 634055, Tomsk
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Review
For citations:
Kornetova E.G., Koval’ S.D., Kornetov A.N., Parshukova D.A., Ivanova S.A., Semke A.V., Gusakova S.V., Bokhan N.A. Brain pathology in schizophrenia: association with clinical and constitutional factors. Yakut Medical Journal. 2019;(1):17-21. https://doi.org/10.25789/YMJ.2019.65.05
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