The prognostic value of cytokine dynamics at Epstein-Barr viral infectious mononucleosis, depending on the age of a child
https://doi.org/10.25789/YMJ.2019.65.02
Abstract
A comprehensive immunological examination of children of different age groups with Epstein-Barr-viral infectious mononucleosis was carried out in order to identify the prognostic value of the cytokine dynamics.
It was revealed that changes in the cytokine profile in 3-6 years old children can be considered as a factor explaining the frequent reactivation of EBV in preschool children. A complex immunological response in 12–17 years old children can be considered the most favorable response to the EBV elimination. The immune response of 7-11 years old children was in an intermediate position.
About the Authors
E. A. Kashuba
Tyumen State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Kashuba Ehduard Alekseevich – PhD, Chief of the Department of infectious diseases
Tyumen
M. V. Antonova
Tyumen State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Antonova Mariya Vladimirovna - Teaching Assistant, the Department of infectious diseases
Tyumen
T. G. Drozdova
Tyumen State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Drozdova Tatyana Georgievna – Candidate of Medical Sciences, the Department of infectious diseases
Tyumen
L. V. Hanipova
Tyumen State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Hanipova Lyudmila Vyacheslavovna - Candidate of Medical Sciences, the Department of infectious diseases
Tyumen
O. A. Ljubimceva
Tyumen State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Lyubimceva Oksana Anatolevna - Candidate of Medical Sciences, the Department of infectious diseases
Tyumen
N. V. Ogoshkova
Tyumen State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Ogoshkova Natalya Vladimirovna - Candidate of Medical Sciences, the Department of infectious diseases
Tyumen
Ju. S. Chehova
Tyumen State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Chehova Julia Sergeevna- Teaching Assistant, the Department of infectious diseases
Tyumen
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Review
For citations:
Kashuba E.A., Antonova M.V., Drozdova T.G., Hanipova L.V., Ljubimceva O.A., Ogoshkova N.V., Chehova J.S. The prognostic value of cytokine dynamics at Epstein-Barr viral infectious mononucleosis, depending on the age of a child. Yakut Medical Journal. 2019;(1):7-10. https://doi.org/10.25789/YMJ.2019.65.02
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