Features of gastrointestinal disorders in children with multisystem inflammatory syndrome associated with COVID-19
https://doi.org/10.25789/YMJ.2022.79.15
Abstract
Resume. Gastrointestinal tract damage is a part of the course of multisystem inflammatory syndrome in children (MVS-D) associated with the new COVID-19 coronavirus infection. According to the results of a retrospective study, gastrointestinal tract damage was detected in 77% of patients with MVS-D and is represented by signs such as abdominal pain, vomiting, diarrhea and peritoneal symptoms. In children with gastrointestinal tract lesions, significant differences were noted in the frequency of occurrence of the following signs: hepatomegaly, splenomegaly, hypotension/shock, as well as conjunctivitis and facial swelling. Among laboratory abnormalities, hypoalbuminemia is more characteristic, but the level of CRP and troponin is higher. The article shows that gastrointestinal tract damage is an important early predictor of the severity of MVS-D.
About the Authors
I. S. Avrusin
Saint Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Avrusin Ilya S. – Senior Research Assistant of the Department of Hospital Pediatrics
K. E. Belozerov
Saint Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Belozerov Konstantin E. – Clinical Resident of the Department of Hospital Pediatrics
O. S. Efremova
Irkutsk Regional Children's Hospital;
Irkutsk State Medical Academy of Postgraduate Education
Russian Federation
Russian Federation
Efremova Olesya S. – Cardiologist, Irkutsk Regional Children's Hospital, Assistant of the Department of Pediatrics of Irkutsk State Medical Academy of Postgraduate Education
L. V. Bregel
Irkutsk State Medical Academy of Postgraduate Education
Russian Federation
Russian Federation
Bregel Lyudmila V. – PhD, MD, Professor, Head of the Department of Pediatrics of Irkutsk State Medical Academy of Postgraduate Education, Chief Pediatric Cardiologist of Irkutsk Region
E. A. Dondurey
St. Petersburg State Medical Institution, N.F. Filatov Children's City Clinical Hospital
Russian Federation
Russian Federation
Dondurey Elena A. – Candidate of Medical Sciences, Head of the Infectious boxed Department of the St. Petersburg State Medical Institution, N.F. Filatov Children's City Clinical Hospital, chief freelance pediatric infectious disease specialist of St. Petersburg
A. A. Vilnits
FSBI DNKCIB;
FMBA of Russia
Russian Federation
Russian Federation
Vilnits Alla A. – PhD, MD, Head of the Research Department of Intensive Care of Emergency Conditions of the FSBI DNKCIB of the FMBA of Russia
K. O. Novgorodova
MI NEFU
Russian Federation
Russian Federation
Novgorodova Kristina O. – the student of the 6th year
T. E. Burtseva
MI NEFU;
YSC CMP
Russian Federation
Russian Federation
Burtseva Tatiana E. – PhD, MD, Professor of the Department of Pediatrics and Pediatric Surgery of MI NEFU, Head of the Laboratory YSC CMP
T. G. Dmitrieva
MI NEFU
Russian Federation
Russian Federation
Dmitrieva Tatiana G. – PhD, MD, Professor of the Department of Pediatrics and Pediatric Surgery
T. L. Kornishina
Saint Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Kornishina Tatiana L. – Assistant of the Department of Hospital Pediatrics
V. V. Masalova
Saint Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Masalova Vera V. – assistant of the Department of Hospital Pediatrics
O. V. Kalashnikova
Saint Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Kalashnikova Olga V. – Candidate of Medical Sciences, Associate Professor of the Department of Hospital Pediatrics
S. L. Avrusin
Saint Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Avrusin Sergey L. – Candidate of Medical Sciences, Associate Professor of the Department of Hospital Pediatrics
O. L. Kolobova
Saint Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Kolobova Oksana L. – Candidate of Medical Sciences, Associate Professor of the Department of Hospital Pediatrics
I. V. Solodkova
Federal State Budgetary Educational Institution of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Solodkova Irina V. – Candidate of Medical Sciences, Associate Professor of the Department of Hospital Pediatrics
V. G. Chasnyk
Saint Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Chasnyk Vyacheslav G. – PhD, MD, Professor, Head of the Department of Hospital Pediatrics
M. M. Kostik
Saint Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Kostik Mikhail M. – chief pediatric rheumatology specialist of the North-Western Federal District of Russia, PhD, MD, Professor of the Department of Hospital Pediatrics
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Review
For citations:
Avrusin I.S., Belozerov K.E., Efremova O.S., Bregel L.V., Dondurey E.A., Vilnits A.A., Novgorodova K.O., Burtseva T.E., Dmitrieva T.G., Kornishina T.L., Masalova V.V., Kalashnikova O.V., Avrusin S.L., Kolobova O.L., Solodkova I.V., Chasnyk V.G., Kostik M.M. Features of gastrointestinal disorders in children with multisystem inflammatory syndrome associated with COVID-19. Yakut Medical Journal. 2022;(3):57-61. https://doi.org/10.25789/YMJ.2022.79.15
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