Acute endothelial cell injury in cardiac surgery patients under artificial blood circulation: the current state of the problem
https://doi.org/10.25789/YMJ.2024.87.21
Abstract
The aim of this study is to summarize studies conducted over the past decades on endothelial damage in cardiac surgery patients who underwent surgical interventions with artificial blood circulation. We searched and analyzed literature on endothelial dysfunction in various medical databases, including PubMed, Cochrane, Elibrary, and Cyberleninka. In addition to medical aspects, our literature review covers historical aspects of the research of endothelial function and dysfunction. We suggest that pathological processes in endothelium during surgery and postoperative period predict adverse treatment outcomes, and therefore should be taken into account by anesthesiologists, resuscitators, cardiac surgeons and transfusiologists. Anaesthetists, cardiologists and transfusionists should take this pathological condition into account during surgical interventions and in the postoperative period due to possible negative impact on treatment outcomes
About the Authors
M. Yu. Kislitsyna
I.P. Pavlov St. Petersburg First State Medical University
Russian Federation
Russian Federation
Kislitsyna Marina Yu. – student
A. V. Mikhailenko
I.P. Pavlov St. Petersburg First State Medical University
Russian Federation
Russian Federation
Mikhailenko Anna V. – student
E. G. Gavrilova
Research Clinical Center of Anesthesiology and Intensive Care; COVID Treatment Medical Center
Russian Federation
Russian Federation
Gavrilova Elena G. – MD, PhD in Medicine, Associate Professor of Anesthesi ology and Intensive Care Department, Head of Anesthesiology and Intensive Care Department No. 2 of the RCC of Anesthesiology and Intensive Care, Head of Intensive Care Department of the COVID Treatment MC
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Review
For citations:
Kislitsyna M.Yu., Mikhailenko A.V., Gavrilova E.G. Acute endothelial cell injury in cardiac surgery patients under artificial blood circulation: the current state of the problem. Yakut Medical Journal. 2024;(3):104-108. https://doi.org/10.25789/YMJ.2024.87.21
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