Clinical, audiological and genealogical analysis of hearing disorders in the Republic of Buryatia
V. G. Pshennikova,
F. M. Teryutin,
N. A. Barashkov,
S. K. Kononova,
A. V. Solovyev,
G. P. Romanov,
S. A. Fedorova https://doi.org/10.25789/YMJ.2020.72.12
Abstract
In this paper we present for the first time the results of the clinical-audiological and genealogical analysis of cases of hearing impairment in the Republic of Buryatia. As a result of the clinical-audiological analysis of the survey sample, the majority of individuals had bilateral deafness of the sensorineural type, the rest had bilateral hearing loss of varying severity. The segregation analysis carried out in Buryat and Russian families made it possible to assume the hereditary nature of cases of hearing impairment, segregating according to an autosomal recessive type of inheritance only in Russian families.
Keywords
clinical-audiological analysis,
clinical-genealogical analysis,
hereditary burden,
hearing impairment,
Republic of Buryatia
Supporting agencies: This study was supported by the Project of the Yakut Scientific Center of Complex Medical Problems “Studying the genetic structure and load of hereditary pathology of populations of the Sakha Republic”, the basic part of the state assignment of the Ministry of Science and Education of the Russian Federation (FSRG-2020-0016) and with the support of RFBR grants (18- 05-600035_ Arctic, 18-015-00212_A, 20- 015-00328_A).
About the Authors
V. G. Pshennikova
Yakut Scientific Center of Сomplex Мedical Рroblems
Russian Federation
Russian Federation
Pshennikova Vera Gennadievna - Ph.D., Head of laboratory
Yakutsk, 677010
F. M. Teryutin
Yakut Scientific Center of Сomplex Мedical Рroblems
Russian Federation
Russian Federation
Teryutin Fedor Mikhailovich - Ph.D., Researcher
Yakutsk, 677010
N. A. Barashkov
Yakut Scientific Center of Сomplex Мedical Рroblems
Russian Federation
Russian Federation
Barashkov Nikolay Alekseevich - Ph.D., Head of laboratory
Yakutsk
S. K. Kononova
Yakut Scientific Center of Сomplex Мedical Рroblems
Russian Federation
Russian Federation
Kononova Sardana Kononovna - Ph.D., Researcher
Yakutsk
A. V. Solovyev
Ammosov of the Institute of Natural Sciences, North-Eastern Federal University
Russian Federation
Russian Federation
Solovyev Aisen Vasilievich - Ph.D., Researcher
Yakutsk, 677010
G. P. Romanov
Institute of Natural Sciences, North-Eastern Federal University
Russian Federation
Russian Federation
Romanov Georgii Prokopievich – Researcher
Yakutsk
S. A. Fedorova
Institute of Natural Sciences, North-Eastern Federal University
Russian Federation
Russian Federation
Fedorova Sardana Arkadievna - Ph.D., Head of Laboratory
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For citations:
Pshennikova V.G., Teryutin F.M., Barashkov N.A., Kononova S.K., Solovyev A.V., Romanov G.P., Fedorova S.A. Clinical, audiological and genealogical analysis of hearing disorders in the Republic of Buryatia. Yakut Medical Journal. 2020;(4):44-49. https://doi.org/10.25789/YMJ.2020.72.12
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