Circulating levels of leptin in blood of young Yakuts depending on the body mass index
A. A. Nikanorova,
N. N. Gotovtsev,
N. A. Barashkov,
V. G. Pshennikova,
S. S. Nakhodkin,
A. V. Solovyev,
S. S. Kuzmina,
N. N. Sazonov,
S. A. Fedorova https://doi.org/10.25789/YMJ.2020.72.04
Abstract
The aim of this study is to evaluate the leptin level circulating in blood serum depending on the body mass index (BMI) in young healthy Yakuts (mean age 19.8±1.5 years). The total sample (n=281) was divided into three groups according to the WHO classification: persons with underweight, normal, overweight / obese. There were no statistically significant differences in BMI between men and women in the groups. As a result of the comparative analysis, it was found that both in women and in men, leptin levels were statistically higher in overweight/obese individuals compared with the other two groups. There were no statistically significant differences in leptin levels between the groups of people with underweight and normal weight, both in women and in men, which could be associated with the body's protection from low temperatures through the development of active brown adipose tissue, secreting additional leptin.
Supporting agencies: The work was done within the scope of the Yakutsk scientific center for complex medical problems "Study of the genetic structure and burden of hereditary pathology of populations of the Republic of Sakha (Yakutia)", the base part of state assignment of Ministry of Science and Higher Education of the Russian Federation (FSRG-2020- 0016) and Russian Foundation for Basic Research (grants #18-05-600035_Arctika).
About the Authors
A. A. Nikanorova
Federal State Budgetary Scientific Institution "Yakut Science Center of Complex Medical Problems"
Russian Federation
Russian Federation
Nikanorova Alеna Afanasyevna – junior researcher, Laboratory of Molecular Genetics
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 89244611585
N. N. Gotovtsev
Federal State Budgetary Scientific Institution "Yakut Science Center of Complex Medical Problems"
Russian Federation
Russian Federation
Gotovtsev Nyurgun Naumovich – Scientific researcher, Laboratory of Molecular Genetics
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 89141062015
N. A. Barashkov
Federal State Budgetary Scientific Institution "Yakutsk Scientific Center of Complex Medical Problems"
Russian Federation
Russian Federation
Barashkov Nikolay Alekseevich – Candidate of biological sciences, Head of laboratory of Molecular genetics
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 8-(4112) 32-19-81
V. G. Pshennikova
Federal State Budgetary Scientific Institution "Yakutsk Scientific Center for Complex Medical Problems"
Russian Federation
Russian Federation
Pshennikova Vera Gennadievna – Candidate of Biological Sciences, Head of laboratory of Populational Genetics
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 8-(4112) 32-19-81
S. S. Nakhodkin
Federal State Autonomous Educational Institution of Higher Education "North-Eastern Federal University M.K. Ammosov"
Russian Federation
Russian Federation
Nakhodkin Sergey Sergeyevich – Engineer-researcher of the Research Laboratory of Molecular Biology Institute of Natural Sciences
677010, Sakha Republic, Yakutsk, Kulakovsky st. 46.
A. V. Solovyev
Federal State Autonomous Educational Institution of Higher Education "North-Eastern Federal University M.K. Ammosov"
Russian Federation
Russian Federation
Solovyev Aisen Vasilyevich – Candidate of Biological Sciences, junior researcher, of the Research Laboratory of Molecular Biology Institute of Natural Sciences
677010, Sakha Republic, Yakutsk, Kulakovsky st. 46.
S. S. Kuzmina
The Institute of Natural Sciences "North-Eastern Federal University M.K. Ammosov"
Russian Federation
Russian Federation
Kuzmina Sargylana Semenovna – Candidate of Biological Sciences, Associate Professor, Department of Biology
677000, Sakha Republic, Yakutsk, Kulakovsky st. 48.
N. N. Sazonov
The Institute of Natural Sciences "North-Eastern Federal University M.K. Ammosov"
Russian Federation
Russian Federation
Sazonov Nikolay Nikitich – Doctor of biological sciences, Professor, Department of Biology
677000, Sakha Republic, Yakutsk, Kulakovsky st. 48.
S. A. Fedorova
Federal State Autonomous Educational Institution of Higher Education "North-Eastern Federal University M.K. Ammosov"
Russian Federation
Russian Federation
Fedorova Sardana Arkadievna – Doctor of biological sciences, Head of the Research Laboratory of Molecular Biology Institute of Natural Sciences
677010, Sakha Republic, Yakutsk, Kulakovsky st. 46.
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Review
For citations:
Nikanorova A.A., Gotovtsev N.N., Barashkov N.A., Pshennikova V.G., Nakhodkin S.S., Solovyev A.V., Kuzmina S.S., Sazonov N.N., Fedorova S.A. Circulating levels of leptin in blood of young Yakuts depending on the body mass index. Yakut Medical Journal. 2020;(4):16-19. https://doi.org/10.25789/YMJ.2020.72.04
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