Prevalence and structure of juvenile idiopathic arthritis in children in the Republic of Sakha (Yakutia)
https://doi.org/10.25789/YMJ.2020.72.01
Abstract
This study was conducted to study the prevalence and structure of juvenile idiopathic arthritis (JIA) in the Republic of Sakha (Yakutia) and to identify some features of this nosology in indigenous children. As a result, the frequency of JIA variants varies in different regions of the RS(Ya), enteritis - associated arthritis being the most commonly noted. Among the features of JIA in indigenous children, there is predominance of male patients, as well as a significantly high hereditary family history. The high frequency of the HLAB27 antigen is associated with JIA in indigenous children twice frequently in Caucasian children.
Keywords
Supporting agencies: The work was done within the framework of the research topic of the FGBU "YSC KMP" SB RAMS, "Monitoring the health status of children in the Republic of Sakha (Yakutia)" (state registration number: 0120-128-07-98), the basic part of the state order of the Ministry of Science and Education of the Russian Federation (FSRG-2020-0016) and with the financial support of the RFBR grant (No. 18-05-60035_Arktika).
About the Authors
F. V. Vinokurova
Yakutsk Scientific Center for Complex Medical Problems (YSC CMP)
Russian Federation
Russian Federation
Vinokurova Fekla Vasilievna – Researcher
V. M. Nikolaev
Yakutsk Scientific Center for Complex Medical Problems (YSC CMP)
Russian Federation
Russian Federation
Nikolaev Vyacheslav Mikhailovich - Candidate of Biological Sciences, Chief Researcher, Head of the Department for the Study of Adaptation Mechanisms
E. K. Rumyantsev
Yakutsk Scientific Center for Complex Medical Problems (YSC CMP)
Russian Federation
Russian Federation
Rumyantsev Egor Konstantinovich - Junior Researcher
T. E. Burtseva
Federal State Autonomous Educational Institution of Higher Education "NorthEastern Federal University named after M.K. Ammosov";
Yakutsk Scientific Center for Complex Medical Problems (YSC CMP)
Russian Federation
Russian Federation
Burtseva Tatyana Egorovna - Doctor of Medical Sciences, Professor of the Department of Pediatrics and Pediatric Surgery of the Medical Institute;
Head of the Laboratory
tel. 8 (914) 2943244
V. M. Argunova
State Autonomous Institution of the Republic of Sakha (Yakutia) "Republican Hospital No. 1 - National Center of Medicine (GAU RS (Y)" RB No. 1-NCM ")
Russian Federation
Russian Federation
Argunova Vera Maichna - Head of the Cardio-Rheumatology Department of the Pediatric Center
P. A. Sleptsova
State Autonomous Institution of the Republic of Sakha (Yakutia) "Republican Hospital No. 1 - National Center of Medicine (GAU RS (Y)" RB No. 1-NCM")
Russian Federation
Russian Federation
Sleptsova Polina Andreevna - Candidate of Medical Sciences, cardio-rheumatologist of the Pediatric Center
V. G. Chasnyk
St. Petersburg State Pediatric Medical University (SPbGPMU)
Russian Federation
Russian Federation
Chasnyk Vyacheslav Grigorievich - Doctor of Medical Sciences, Head. Department of Hospital Pediatrics
M. M. Kostik
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Kostik Mikhail Mikhailovich - Doctor of Medical Sciences, Professor of the Department of Hospital Pediatrics
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Review
For citations:
Vinokurova F.V., Nikolaev V.M., Rumyantsev E.K., Burtseva T.E., Argunova V.M., Sleptsova P.A., Chasnyk V.G., Kostik M.M. Prevalence and structure of juvenile idiopathic arthritis in children in the Republic of Sakha (Yakutia). Yakut Medical Journal. 2020;(4):6-9. https://doi.org/10.25789/YMJ.2020.72.01
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