Changes in the progesterone synthetic function of the villous chorion in cytomegalovirus infection as one of the factors of the threatened miscarriage in early pregnancy
https://doi.org/10.25789/YMJ.2020.70.02
Abstract
100 villous chorions at 9-12 weeks of pregnancy were studied in order to identify the relationship between the indicators of progesterone synthetic activity of the fetoplacental complex being formed and the nature of clinical and echographic manifestations of the threatened miscarriage in groups of women with different course of cytomegalovirus infection (CMV) infection. It was identified a significant dependence of the frequency of the threatened miscarriage and its clinical and echographic manifestations on the exacerbation of CMV infection in the first trimester of pregnancy, which was combined with low values of progesterone and 3β-hydroxy-5-pregnen-20-one-dehydrogenase in the villous chorion compared to the group with a latent course of infection.
About the Authors
I. V. Dovzhikova
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Inna V. Dovzhikova – PhD, D.Sc. (Biol.), Leading Staff Scientist of Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases
22 Kalinina Str., Blagoveshchensk, 675000
I. A. Andrievskaya
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Irina A. Andrievskaya – PhD, D.Sc. (Biol.), Professor RAS, Head of Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases
22 Kalinina Str., Blagoveshchensk, 675000
K. K. Petrova
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Kseniya K. Petrova – MD, obstetrician-gynecologist of the paid medical services department FESC PPR
22 Kalinin Str., Blagoveschensk, 675000
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Review
For citations:
Dovzhikova I.V., Andrievskaya I.A., Petrova K.K. Changes in the progesterone synthetic function of the villous chorion in cytomegalovirus infection as one of the factors of the threatened miscarriage in early pregnancy. Yakut Medical Journal. 2020;(2):10-12. https://doi.org/10.25789/YMJ.2020.70.02
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