Features of clinical manifestations and cytokine regulation in gastritis in schoolchildren with familial predisposition to the peptic ulcer disease
https://doi.org/10.25789/YMJ.2021.73.33
Abstract
Schoolchildren of Siberia (Tyva, Evenkia, Aginsky Buryatsky National District, Krasnoyarsk city) with gastrointestinal complaints were examined. Aim: to study the features of clinical manifestations and indicators of circulating cytokines in gastritis in schoolchildren with familial predisposition to the peptic ulcer disease.
It was found out that in children with familial predisposition, gastritis occurs with the involvement of the systemic level of cytokine regulation (expression of IL-4, IFN-α). Moreover, in children with H. pylori infection, the cytokine regulation of the inflammatory process is specific (TNM-α expression).
About the Authors
T. V. Polivanova
Scientific Research Institute for Medical Problems of the North of Federal Research Centre «Krasnoyarsk Scientific Centre» of Siberian Division of Russian Academy of Sciences
Russian Federation
Russian Federation
Polivanova Tamara Vladimirovna – Doctor of Medicine, Chief Researcher of Clinical Department of the Pathology of Digestion System in Adults and Children
V. A. Vshivkov
Scientific Research Institute for Medical Problems of the North of Federal Research Centre «Krasnoyarsk Scientific Centre» of Siberian Division of Russian Academy of Sciences
Russian Federation
Russian Federation
Vshivkov Vitaliy Alekseevich - PhD (Medicine), Senior Researcher of Clinical Department of the Pathology of Digestion System in Adults and Children
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Review
For citations:
Polivanova T.V., Vshivkov V.A. Features of clinical manifestations and cytokine regulation in gastritis in schoolchildren with familial predisposition to the peptic ulcer disease. Yakut Medical Journal. 2021;(2):129-133. https://doi.org/10.25789/YMJ.2021.73.33
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