The relationship between markers of bone remodeling and the risk of bone fracture in patients with rheumatoid arthritis
https://doi.org/10.25789/YMJ.2021.74.31
Abstract
The aim of the study is to study the possibility of predicting bone fractures by determining the concentration of markers of bone remodeling in patients with rheumatoid arthritis (RA). The diagnostic value of laboratory determination of bone remodeling markers (CrossLaps, P1NP and 25-OH vitamin D in serum) was studied using a characteristic curve (ROC curve). It was found that laboratory determination of type I collagen C-telopeptide for predicting the risk of fractures in RA is of good quality.
About the Authors
Yu. R. Akhverdyan
FSBI “RICER named after A.B. Zborovsky”
Russian Federation
Russian Federation
Akhverdyan Yuri Rubenovich - PhD in Medicine, Senior Researcher at the Laboratory of Methods for the Treatment and Prevention of Joint Diseases
B. V. Zavodovsky
Federal State Budget Scientific Institution Scientific Research Institute of the FSBI “RICER named after A.B. Zborovsky”
Russian Federation
Russian Federation
Zavodovsky Boris Valerievich - Doctor of Medical Sciences, Deputy Director for Research
the head. laboratory of methods of treatment and prevention of joint diseases
Yu. V. Polyakova
FSBI “RICER named after A.B. Zborovsky”
Russian Federation
Russian Federation
Polyakova Yulia Vasilievna - PhD in Medicine, Researcher
L. E. Sivordova
FSBI “RICER named after A.B. Zborovsky”
Russian Federation
Russian Federation
Sivordova Larisa Evgenievna - PhD in Medicine, leading researcher at the laboratory of methods for the treatment and prevention of joint diseases
E. V. Papichev
FSBI “RICER of A.B. Zborovsky”
Russian Federation
Russian Federation
Papichev Evgeny Vasilievich - Junior Researcher at the Laboratory for Methods of Treatment and Prevention of Joint Diseases
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Review
For citations:
Akhverdyan Yu.R., Zavodovsky B.V., Polyakova Yu.V., Sivordova L.E., Papichev E.V. The relationship between markers of bone remodeling and the risk of bone fracture in patients with rheumatoid arthritis. Yakut Medical Journal. 2021;(2):120-122. https://doi.org/10.25789/YMJ.2021.74.31
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