The role of HOXA gene aberrant expression of in the genesis of gynecological diseases
https://doi.org/10.25789/YMJ.2021.74.28
Abstract
The review presents current data on the effect of endometrial expression of the homeobox genes HOXA10 and HOXA11 on implantation processes in healthy fertile women and in common gynecological diseases. The features of gene expression, potentially unfavorable for implantation and leading to infertility are described. The variability of receptivity markers expression before and after myomectomy, salpingectomy and the removal of ovarian endometriomas was shown.
About the Authors
E. G. Chukhnina
FSBEI HE SUSMU of the Ministry of Health of Russia
Russian Federation
Russian Federation
Chukhnina Elena Galievna – Postgraduate at Department of Pathological Anatomy and Forensic Medicine
Chelyabinsk
M. L. Polina
Women's Health Medical Center
Russian Federation
Russian Federation
Polina Miroslava Leonidovna – PhD in Medical Sciences, Gynecologist
Moscow
N. I. Douglas
Medical Institute of North-Eastern Federal University
Russian Federation
Russian Federation
Douglas Natalya Ivanovna – Grand PhD in Medical Sciences, Head of the Department of Obstetrics and Gynecology
Yakutsk
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Review
For citations:
Chukhnina E.G., Polina M.L., Douglas N.I. The role of HOXA gene aberrant expression of in the genesis of gynecological diseases. Yakut Medical Journal. 2021;(2):108-112. https://doi.org/10.25789/YMJ.2021.74.28
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