Etiological and pathogenetic characteristics, treatment and prevention of inflammatory periodontal diseases
https://doi.org/10.25789/YMJ.2022.78.09
Abstract
A review of the literature on the etiological and pathogenetic mechanisms of the development of periodontitis was carried out. The main known etiological and pathogenetic mechanisms for the development of periodontitis require further research in order to expand theoretical concepts that will improve the treatment and prevention measures and improve the quality of life of patients.
About the Authors
O. S. Unusyan
Federal State Autonomous Educational Institution of Higher Education "M.K. Ammosov North-Eastern Federal University"
Russian Federation
Russian Federation
Unusyan Onik Sarkisovich – Postgraduate of the Department of Therapeutic, Surgical, Orthopedic Dentistry and Childhood Dentistry of the Medical Institute
I. D. Ushnitsky
Federal State Autonomous Educational Institution of Higher Education "M.K. Ammosov North-Eastern Federal University"
Russian Federation
Russian Federation
Ushnitsky Innokentiy Dmitrievich – Head of the Department of Therapeutic, Surgical, Orthopedic Dentistry and Childhood
Dentistry of the Medical Institute, Doctor of Medical Sciences, Professor
Ya. A. Akhremenko
Federal State Autonomous Educational Institution of Higher Education "M.K. Ammosov North-Eastern Federal University"
Russian Federation
Russian Federation
Akhremenko Yana Aleksandrovna – Candidate of Medical Sciences, Docent, Associate Professor of the Department of Histology and Microbiology of the Medical Institute
K. V. Komzin
Federal State Autonomous Educational Institution of Higher Education "M.K. Ammosov North-Eastern Federal University"
Russian Federation
Russian Federation
Komzin Kirill Vasilevich – Senior Lecturer of the Department of Histology and Microbiology of the Medical Institute
T. S. Varzhapetyan
Federal State Autonomous Educational Institution of Higher Education "M.K. Ammosov North-Eastern Federal University"
Russian Federation
Russian Federation
VarzhapetyanTigran Sosovich – Student of Economic and Financial Institute
Tel: +79142727774
L. S. Unusyan
Federal State Autonomous Educational Institution of Higher Education "M.K. Ammosov North-Eastern Federal University"
Russian Federation
Russian Federation
UnusyanLarisa Sarkisovna – Student of the Medical Institute
References
1. Clinical and epidemiological characteristics of pathological processes, inflammatory-destructive nature of periodontal tissues / Ushnitsky I.D., Ivanov A.V., Ivanova A.A., Yurkevich A.V., Seydalova E.M., Novogodin A.A. // Yakut medical journal. 2018; (61):83-86. DOI: 10.25789/YMJ.2018.61.25
2. Pat. 2751809 Russian Federation. Method of treatment of periodontitis / Ushnitskii ID, Unusian OS, Ivanova AA, Akhremenko IaA, Ivanov AV, Shashurin MM, Kershengolts BM, Unusian LS; applicant and patentee Federal State Autonomous Educational Institution of Higher Education, Ammosov North-Eastern Federal University» decl. 18.12.2020; publ. 19.07.21, bul.№20.
3. Pat. 2751810 Russian Federation. Method of treatment of chronic periodontitis / Ushnitskii ID, Unusian OS, Ivanova AA [et al.]; applicant and patentee Federal State Autonomous Educational Institution of Higher Education «M. K. Ammosov North-Eastern Federal University» decl. 18.12.2020; publ. 19.07.21, bul.№20.
4. Characteristics of risk factors for the formation and development of pathological processes of periodontal tissues of inflammatory-destructive character in the population living in the conditions of the North / Ivanov A.V., Ushnitsky I. D., Yurkevich A.V. [et al.] // Yakut medical journal. 2020; (71):92-95. DOI: 10.25789/YMJ.2020.71.24
5. Frequency and structure of pathological processes of periodontal tissues of an inflammatory and destructive nature in the population of the far Eastern region / Suvirina M.B., Ushnitsky I.D., Yurkevich A.V. [et al.] // Yakut medical journal. 2018; (63):71-74. DOI: 10.25789/YMJ.2018.63.24
6. Abusleme L, Hoare A, Hong B-Y, Diaz PI. Microbial signatures of health, gingivitis and periodontitis. Periodontol 2000. 2021;(86):57-78 DOI: 10.1111/prd.12362
7. Ardila CM, Guzmán IC. Association of Porphyromonas gingivalis with high levels of stress-induced hormone cortisol in chronic periodontitis patients. J Investig Clin Dent. 2016;(7):361-367. DOI: 10.1111/jicd.12175
8. Belstrøm D, Grande MA, Sembler-Møller ML, Kirkby N, Cotton SL, Paster BJ, Holmstrup P. Influence of periodontal treatment on subgingival and salivary microbiotas. J Periodontol. 2018;(89):531-539. DOI: 10.1002/JPER.17-0377
9. Bowen WH, Burne RA, Wu H, Koo H. Oral biofilms: pathogens, matrix, and polymicrobial interactions in microenvironments. Trends Microbiol. 2018;(26):229-242. DOI: 10.1016/j.tim.2017.09.008.
10. Chen C, Hemme C, Beleno J, Shi ZJ, Ning D, Qin Y, Tu Q, Jorgensen M, He Z, Wu L, Zhou J. Oral microbiota of periodontal health and disease and their changes after nonsurgical periodontal therapy. Ismej. 2018;(12):1210-1224. DOI:10.1038/s41396-017-0037-1.
11. Chen Y-YM, Chiang Y-C, Tseng T-Y, et al. Molecular and functional analysis of the type IV pilus gene cluster in Streptococcus sanguinis SK36. Appl Environ Microbiol. 2019;(85): 02788-18. DOI: 10.1128/AEM.02788-18.
12. Cieplik F, Kara E, Muehler D, et al. Antimicrobial efficacy of alternative compounds for use in oral care toward biofilms from caries-associated bacteria in vitro. Microbiology Open. 2019;(8):00695. DOI: 10.1002/mbo3.695
13. Cosgarea R, Juncar R, Heumann C, Tristiu R, Lascu L, Arweiler N, Stavropoulos A, Sculean A. Non-surgical periodontal treatment in conjunction with 3 or 7 days’ systemic administration of amoxicillin and metronidazole in severe chronic periodontitis patients. A placebo-controlled randomized clinical study. J Clin Periodontol. 2016;(43):767-777. DOI: 10.1111/jcpe.12559
14. Couvigny B, Kulakauskas S, Pons N, et al. Identification of new factors modulating adhesion abilities of the pioneer commensal bacterium Streptococcus salivarius. Front Microbiol. 2018;(9):273. DOI: 10.3389/fmicb.2018.00273
15. Dominy SS, Lynch C, Ermini F, et al. Porphyromonas gingivalis in Alzheimer's disease brains: evidence for disease causation and treatment with small-molecule inhibitors. Sci Adv. 2019;(5):3333. DOI: 10.1126/sciadv.aau3333
16. Ebersole JL, Peyyala R, Gonzalez OA. Biofilm-induced profiles of immune response gene expression by oral epithelial cells. Mol Oral Microbiol. 2019;(34):14-25. DOI: 10.1111/omi.12251
17. Graves DT, Corrêa JD, Silva TA. The oral microbiota is modified by systemic diseases. J Dent Res. 2019;(98):148-156. DOI: 10.1177/0022034518805739
18. Han J, Wang P, Ge S. The microbial community shifts of subgingival plaque in patients with generalized aggressive periodontitis following non-surgical periodontal therapy: a pilot study. Oncotarget. 2017;(8):10609-10609. DOI: 10.18632/oncotarget.12532
19. Hathaway-Schrader J, Novince C. Maintaining homeostatic control of periodontal bone tissue. Periodontol 2000. 2021;(86):157–187 DOI: 10.1111/prd.12368
20. Jiao J, Shi D, Cao Z-Q, Meng H-X, Lu R-F, Zhang L, Song Y, Zhao J-R. Effectiveness of non-surgical periodontal therapy in a large Chinese population with chronic periodontitis. J Clin Periodontol. 2017;(44): 42-50. DOI: 10.1111/jcpe.12637
21. Kaan A, Kahharova D, Zaura E. The acquisition and establishment of the oral microbiota. Periodontol 2000. 2021;(86):116-134. DOI: 10.1111/prd.12366
22. Kim YJ, Park JM, Cho HJ, Ku Y. Correlation analysis of periodontal tissue dimensions in the esthetic zone using a non-invasive digital method. J Periodontal Implant Sci. 2021;(51):88-99. DOI: 2003460173
23. Kinane DF, Stathopoulou PG, Papapanou PN. Periodontal diseases. Nat Rev Dis Primer. 2017;(3):17038-17039. DOI: 10.1038/nrdp.2017.38
24. Lamont RJ, Koo H, Hajishengallis G. The oral microbiota: dynamic communities and host interactions. Nat Rev Microbiol. 2018;(16):745-759. DOI: 10.1038/s41579-018-0089-x
25. Martinez-Canut P. Predictors of tooth loss due to periodontal disease in patients following long-term periodontal maintenance. J Clin Periodontol. 2015;(42):1115-1125. DOI: 10.1111/jcpe.12475
26. Martins SHL. Effect of surgical periodontal treatment associated to antimicrobial photodynamic therapy on chronic periodontitis: a randomized controlled clinical trial. J Clin Periodontol. 2017;(44):717-728. DOI: 10.1111/jcpe.12744
27. Moutsopoulos NM, Konkel JE. Tissue-specific immunity at the oral mucosal barrier. Trends Immunol. 2018;(39):276-287 DOI: 10.1016/j.it.2017.08.005
28. Murakami Y, Hasegawa Y, Nagano K, Yoshimura F. Characterization of wheat germ agglutinin lectin-reactive glycosylated OmpA-like proteins derived from Porphyromonas gingivalis. Infect Immun. 2014;(82):4563-4571. DOI: 10.1128/IAI.02069-14
29. Payne MA, Hashim A, Alsam A, et al. Horizontal and vertical transfer of oral microbial dysbiosis and periodontal disease. J Dent Res. 2019;(98):1503-1510. DOI: 10.1177/0022034519877150
30. Pretzl B, Sälzer S, Ehmke B, et al. Administration of systemic antibiotics during non-surgical periodontal therapy a consensus report. Clin Oral Investig. 2018;(93):1-13. DOI: 10.1007/s00784-018-2727-0
31. Radini A, Nikita E, Buckley S, Copeland L, Hardy K. Beyond food: the multiple pathways for inclusion of materials into ancient dental calculus. Am J Phys Anthropol. 2017;(l63):71-83. DOI: 10.1098/rspb.2018.0977
32. Schulz S, Porsch M, Grosse I, Hoffmann K, Schaller HG, Reichert S. Comparison of the oral microbiome of patients with generalized aggressive periodontitis and periodontitis-free subjects. Arch Oral Biol. 2019;(99):169-176. DOI: 10.1016/j.archoralbio.2019.01.015
33. Shi M, Wei Y, Hu W, Nie Y, Wu X, Lu R. The subgingival microbiome of periodontal pockets with different probing depths in chronic and aggressive periodontitis: a pilot study. Front Cell Infect Microbiol. 2018;(8):124-125. DOI: 10.3389/fcimb.2018.00124
34. Shrivastava A, Patel VK, Tang Y, Yost SC, Dewhirst FE, Berg HC. Cargo transport shapes the spatial organization of a microbial community. Proc Natl Acad Sci USA. 2018;(115):8633-8638. DOI: 10.1073/pnas.1808966115
35. Stein JM, Lintel-Höping N, Hammächer C, Kasaj A, Tamm M, Hanisch O. The gingival biotype: measurement of soft and hard tissue dimensions – a radiographic morphometric study. J Clin Periodontol 2013;(40):1132–1139. DOI: 10.1111/jcpe.12169.
36. Van der Weijden GA, Dekkers GJ, Slot DE. Success of non-surgical periodontal therapy in adult periodontitis patients- A retrospective analysis. Int J Dent Hyg.2019;(17):309-317. DOI: 10.1111/idh.12399
37. Velsko IM, Shaddox LM. Consistent and reproducible longterm in vitro growth of health and disease-associated oral subgingival biofilms. BMC Microbiol.2018;(18):70. DOI: 10.1186/s12866-018-1212-x
38. Wade WG. The resilience of the oral microbiome. Periodontol 2000.2021;(86):113-122. DOI: 10.1111/prd.12365
Review
For citations:
Unusyan O.S., Ushnitsky I.D., Akhremenko Ya.A., Komzin K.V., Varzhapetyan T.S., Unusyan L.S. Etiological and pathogenetic characteristics, treatment and prevention of inflammatory periodontal diseases. Yakut Medical Journal. 2022;(2):36-41. https://doi.org/10.25789/YMJ.2022.78.09
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