Browning markers in adult indigenous residents of Yakutia in conditions of natural cold
https://doi.org/10.25789/YMJ.2021.76.23
Abstract
In this work the expression profile in peripheral blood mononuclear cells of markers of brown adipose tissue activity (CIDEA, PRDM 16), markers of browning of white adipocytes (HOXC9, Slc27A1) and the marker of β-oxidation of fatty acids (Cpt1a) was analyzed in 150 indigenous residents of Yakutia, miners of a diamond mining company, who were exposed to natural cold for 3 months. To determine the metabolic status, anthropometric data, glucose level and blood lipid profile of were evaluated.
About the Authors
A. V. Efremova
Yakutsk Science Centre of Complex medical problems
Russian Federation
Russian Federation
Efremova Agrafena Vladimirovna – Candidate of Biological Sciences, senior researcher
V. A. Alekseev
Yakutsk Science Centre of Complex medical problems
Russian Federation
Russian Federation
Alekseev Vladislav Amirovich – junior researcher
A. A. Grigorieva
Yakutsk Science Centre of Complex medical problems
Russian Federation
Russian Federation
Grigorieva Anastasia Anatolyevna – junior researcher
S. Cinti
Polytechnic University del Marche
Italy
Italy
Cinti Saverio, MD, Prof., Director of the Center for Obesity Study
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Review
For citations:
Efremova A.V., Alekseev V.A., Grigorieva A.A., Cinti S. Browning markers in adult indigenous residents of Yakutia in conditions of natural cold. Yakut Medical Journal. 2021;(4):97-103. https://doi.org/10.25789/YMJ.2021.76.23
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