Creation of a model of ovarian cancer in immunodeficient mice of the Balb / c Nude line
https://doi.org/10.25789/YMJ.2021.74.04
Abstract
The purpose of this study was to create an in vivo model of ovarian cancer allowing control of the dynamics of tumor growth and adequate data on its size. As a model Balb/c Nude mouse lines were used. Removal of the mouse ovary with an implanted tumor fragment under the skin made it easier to visualize and to control the dynamics of xenograft growth.
About the Authors
O. I. Kit
National Medical Research Centre for Oncology
Russian Federation
Russian Federation
Kit Oleg I. – D.Med.Sci., General Director
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
E. V. Verenikina
National Medical Research Centre for Oncology
Russian Federation
Russian Federation
Verenikina Ekaterina V. – Cand.Med.Sci., Head of Department of Oncogynecology
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
M. V. Mindar
National Medical Research Centre for Oncology
Russian Federation
Russian Federation
Mindar Maria V. – junior researcher
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
E. A. Likbanova
National Medical Research Centre for Oncology
Russian Federation
Russian Federation
Likbanova Ekaterina A. – researcher
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
E. M. Nepomnyashchaya
National Medical Research Centre for Oncology
Russian Federation
Russian Federation
Nepomnyashchaya Evgenia M. – pathologist, Pathoanatomical Department, D.Med.Sci.
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
A. P. Menshenina
National Medical Research Centre for Oncology
Russian Federation
Russian Federation
Menshenina Anna P. – leading researcher, Section of Reproductive Tumors, Cand.Med.Sci.
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
M. L. Adamyan
National Medical Research Centre for Oncology
Russian Federation
Russian Federation
Adamyan Meri L. – researcher, Section of Reproductive Tumors, Cand.Med.Sci.
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
M. M. Kecheryukova
National Medical Research Centre for Oncology
Russian Federation
Russian Federation
Kecheryukova Madina M. – postgraduate student
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
A. Yu. Ardzha
National Medical Research Centre for Oncology
Russian Federation
Russian Federation
Ardzha Anna Yu. - oncologist, Cand.Med.Sci.
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
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Review
For citations:
Kit O.I., Verenikina E.V., Mindar M.V., Likbanova E.A., Nepomnyashchaya E.M., Menshenina A.P., Adamyan M.L., Kecheryukova M.M., Ardzha A.Yu. Creation of a model of ovarian cancer in immunodeficient mice of the Balb / c Nude line. Yakut Medical Journal. 2021;(2):17-20. https://doi.org/10.25789/YMJ.2021.74.04
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