Physical and sexual development of boys with latent iron deficiency
https://doi.org/10.25789/YMJ.2023.82.07
Abstract
The aim of the study was to analyze the possible impact of iron deficiency without anemia on physical and sexual development of adolescent boys.
Physical development of adolescent boys with iron deficiency without anemia did not differ from that of their healthy peers. Iron deficiency without anemia did not altered physical development of adolescent boys. Obesity or excess weight is associated with a higher serum ferritin level, which should be considered when diagnosing iron deficiency. Iron deficiency is associated with sower sexual development in boys.
Keywords
About the Authors
E. A. BalashovaRussian Federation
Samara
M. Yu. Gavryushin
Russian Federation
Samara
I. L. Shadrina
Russian Federation
Samara
References
1. Bioimpedance analysis of human body composition / Nikolaev D.V. [et al.]. Moscow, 2009. 392 p.
2. Age estimation of the latent deficiency iron condition of the children in Tyumen region / Sharuho G.V. [et al.] // Medical science and education of Ural. 2009. Vol. 10. 2(57). P. 46-48.
3. Durmanov N.D., Filimonov A.S. Diagnosis and Correction of Iron Metabolism Disorders in Elite Sports: Guidelines for Club Doctors. Moscow. 2010. 84 p.
4. Yerbaktanova T.A. Reproductive health of adolescent girls in the Tyumen Region against the background of latent iron deficiency : dis. … of PhD in Medicine: 14.01.08, 14.01.01: defense of the thesis 05.06.2014. Tyumen. 2014. - 23 p.
5. Mazurin A.V., Voroncov I.M. Propedeutics of childhood diseases. 3<sup>d</sup> ed., Saint Petersburg; 2009. 1008 p.
6. Melnikov V.M., Samykina O.V., Skvorchevskaja S.A. The prevalence of latent iron deficiency in infertile women of Samara City [electronic resource]. Modern problems of science and education. 2013. 1. Available at: https://science-education.ru/ru/article/view?id=8349
7. Samkina O.N., Vodovozova Je.V., Ledeneva L.N., Rogov A.V. Epidemiology of iron deficiency anemia in children of Stavropol Region according to data of oncohematology department GBUZ SK "KDKB". Russian Bulletin of Perinatology and Pediatrics. 2018; 4(63): 188.
8. Risk factors of development of iron-deficiency conditions in Moscow adolescents / Zakharova I.N. [et al.] // Pediatric pharmacology. 2015. 12 (5): 609–613. doi: 10.15690/pf.v12i5.1464.
9. Gavryushin M.Y. [et al.] Physical development of children and adolescents of school age : textbook. Moscow, 2019. – 83 p.
10. Antenatal Iron-Folic Acid Supplementation Is Associated with Improved Linear Growth and Reduced Risk of Stunting or Severe Stunting in South Asian Children Less than Two Years of Age: A Pooled Analysis from Seven Countries / Nisar YB. [et al.] // Nutrients. 2020. Vol. 12(9). P. 2632. doi: 10.3390/nu12092632.
11. Body fat reference curves for children / McCarthy HD. [et al.] // Int J Obes. 2006. Vol. 30. P. 598–602. doi: 10.1038/sj.ijo.0803232
12. Chronic Iron Deficiency and Cognitive Function in Early Childhood / Gingoyon A. [et al.] // Pediatrics. 2022. Vol. 150(6). P. e2021055926. doi: 10.1542/peds.2021-055926
13. Effects of Iron Supplementation on Testicular Function and Spermatogenesis of Iron-Deficient Rats / Tsao CW. [et al.] // Nutrients. 2022. Vol. 14 (10). P. 2063. doi: 10.3390/nu14102063.
14. Gabrielsen JS., Lamb DJ., Lipshultz LI. Iron and a Man's Reproductive Health: the Good, the Bad, and the Ugly // Curr Urol Rep. 2018. Vol. 19 (8). P. 60. doi: 10.1007/s11934-018-0808-x.
15. Gedfie S, Getawa S, Melku M. Prevalence and Associated Factors of Iron Deficiency and Iron Deficiency Anemia Among Under-5 Children : A Systematic Review and Meta-Analysis // Glob Pediatr Health. 2022. 9. 2333794X221110860. doi: 10.1177/2333794X221110860.
16. Hypogonadism in male thalassemia major patients: pathophysiology, diagnosis and treatment / De Sanctis V. [et al.] // Acta Biomed. 2018. Vol. 89 (2-S). P. 6-15. doi:10.23750/abm.v89i2-S.7082
17. Iron deficiency anemia and megaloblastic anemia in obese patients / Arshad M. [et al.] // Rom J Intern Med. 2017. Vol. 55 (1). P. 3-7. doi: 10.1515/rjim-2016-0046.
18. Iron Metabolism in Obesity and Metabolic Syndrome / González-Domínguez A. [et al.] // Int J Mol Sci. 2020. Vol. 21 (15). P. 5529. doi: 10.3390/ijms21155529.
19. Kumar V, Choudhry VP. Iron deficiency and infection // Indian J Pediatr. 2010. Vol. 77(7). P. 789-793. doi: 10.1007/s12098-010-0120-3
20. Nutrition, genetic variation and male fertility / Vanderhout SM. [et al.] // Transl Androl Urol. 2021. Vol. 10 (3). P. 1410-1431. doi: 10.21037/tau-20-592
21. Obesity in young children and its relationship with diagnosis of asthma, vitamin D deficiency, iron deficiency, specific allergies and flat-footedness : A systematic review and meta-analysis / Malden S. [et al.] // Obes Rev. 2021. Vol. 22 (3). P. e13129. doi: 10.1111/obr.13129.
22. Pubertal Development and its Determinants in Adolescents With Transfusion-Dependent Thalassemia / Singh P. [et al.] // Indian Pediatr. 2021. Vol. 58 (7). P. doi:635-638. doi: 10.1007/s13312-021-2258-7
23. Relationship between Obesity and Iron Deficiency in Healthy Adolescents / Ortíz Pérez M. [et al.] // Child Obes. 2020. Vol. 16 (6). P. 440-447. doi: 10.1089/chi.2019.0276.
24. The Hepcidin and 25-OH-Vitamin D Levels in Obese Children as a Potential Mediator of the Iron Status / Aka S. [et al.] // Clin Lab. 2021. Vol. 67 (5). P. 10.7754/Clin.Lab.2020.200813. doi: 10.7754/Clin.Lab.2020.200813.
25. World Health Organization. Nutritional anaemias: tools for effective prevention and control [electronic resource]. Geneva: World Health Organization; 2017. Available at: https://www.who.int/publications/i/item/9789241513067
26. Zheng J, Liu J, Yang W. Association of Iron-Deficiency Anemia and Non-Iron-Deficiency Anemia with Neurobehavioral Development in Children Aged 6-24 Months // Nutrients. 2021. Vol. 13(10). P. 3423. doi: 10.3390/nu13103423
Review
For citations:
Balashova E.A., Gavryushin M.Yu., Shadrina I.L. Physical and sexual development of boys with latent iron deficiency. Yakut Medical Journal. 2023;(2):29-33. https://doi.org/10.25789/YMJ.2023.82.07