Correlation analysis of the immunological and clinical parameters of patients with endo-periodontal lesions
https://doi.org/10.25789/YMJ.2025.89.09
Abstract
Inflammatory processes occurring in the pulp and periodontal tissues can cause both auto- and heterosensitization of the body, which in turn leads to a decrease in its immune defense. In order to determine the effectiveness of studying the level of cytokines in the diagnosis of endo-periodontal lesions, we compared clinical and immunological parameters in 82 patients with endo-periodontal lesions and 47 periodontally healthy individuals aged 23-54 years. As a result of the study, a correlation was found between the severity of inflammatory processes in periodontal tissues and the level of proinflammatory cytokines. Statistically significant differences were found in the concentration of TNF-α and IL-6 in the oral fluid of patients with EPL depending on the severity of periodontal damage, which emphasizes the role of these cytokines in the progression of the disease.
About the Authors
E. V. Krikun
Казанский гос. медицин. ун-т МЗ РФ
Russian Federation
Russian Federation
S. L. Blashkova
Казанский гос. медицин. ун-т МЗ РФ
Russian Federation
Russian Federation
I. Kh. Valeeva
Казанский гос. медицин. ун-т МЗ РФ
Russian Federation
Russian Federation
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Review
For citations:
Krikun E.V., Blashkova S.L., Valeeva I.Kh. Correlation analysis of the immunological and clinical parameters of patients with endo-periodontal lesions. Yakut Medical Journal. 2025;(1):36-39. https://doi.org/10.25789/YMJ.2025.89.09
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