Роль андрогенов в патогенезе рака эндометрия
Т. И. Моисеенко,
Е. М. Франциянц,
А. П. Меньшенина,
В. А. Бандовкина,
М. Л. Адамян,
М. А. Рогозин,
Н. Д. Черярина https://doi.org/10.25789/YMJ.2024.85.24
Аннотация
Рак эндометрия за последние десятилетия по заболеваемости вышел на первое место в рейтинге онкогинекологических заболеваний во всем мире. Исследования последних лет показывают стероидозависимость рака эндометрия не только от эстрогенов, но и от андрогенов, непосредственно участвующих в сложных процессах трансформации в эстрогены. Опубликованные данные в достаточной степени противоречивы, неоднозначны, подтверждают антипролиферативную роль андрогенов в патогенезе рака тела матки. Настоящий обзор посвящен анализу публикаций, касающихся роли андрогенов в патогенезе и возможном клиническом противоопухолевом применении андрогенов.
Об авторах
Т. И. Моисеенко
Национальный медицин. исслед. центр онкологии МЗ РФ
Россия
Россия
МОИСЕЕНКО Татьяна Ивановна – д.м.н., проф., гл.н.с.
Е. М. Франциянц
Национальный медицин. исслед. центр онкологии МЗ РФ
Россия
Россия
ФРАНЦИЯНЦ Елена Михайловна – д.б.н., проф., зам. ген. дир.
А. П. Меньшенина
Национальный медицин. исслед. центр онкологии МЗ РФ
Россия
Россия
МЕНЬШЕНИНА Анна Петровна – д.м.н., в.н.с.
В. А. Бандовкина
Национальный медицин. исслед. центр онкологии МЗ РФ
Россия
Россия
БАНДОВКИНА Валерия Ахтямовна – д.б.н., с.н.с.
М. Л. Адамян
Национальный медицин. исслед. центр онкологии МЗ РФ
Россия
Россия
АДАМЯН Мери Людвиковна – к.м.н., н.с.
М. А. Рогозин
Национальный медицин. исслед. центр онкологии МЗ РФ
Россия
Россия
РОГОЗИН Марк Андреевич – аспирант
Н. Д. Черярина
Национальный медицин. исслед. центр онкологии МЗ РФ
Россия
Россия
ЧЕРЯРИНА Наталья Дмитриевна – врач-лаборант
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Рецензия
Для цитирования:
Моисеенко Т.И., Франциянц Е.М., Меньшенина А.П., Бандовкина В.А., Адамян М.Л., Рогозин М.А., Черярина Н.Д. Роль андрогенов в патогенезе рака эндометрия. Якутский медицинский журнал. 2024;(1):97-101. https://doi.org/10.25789/YMJ.2024.85.24
For citation:
Moiseenko T.I., Frantsiyants E.M., Menshenina A.P., Bandovkina V.A., Adamyan L.M., Rogozin M.A., Cheryarina N.D. The role of androgens in the pathogenesis of endometrial cancer. Yakut Medical Journal. 2024;(1):97-101. https://doi.org/10.25789/YMJ.2024.85.24
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