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Quality of health of hospitalized COVID-19 patients in the post-COVID period: a two-year follow-up

https://doi.org/10.25789/YMJ.2023.84.20

Abstract

Accumulating evidence indicates a high prevalence of long-term negative consequences of COVID-19. Their final assessment is possible only after their complete disappearance, which, given the ongoing registration of negative assessments of the health status of some hospitalized COVID-19 patients, is impossible in the near future. Taking this into account, further study of post-Covid consequences in dynamics is relevant. The purpose of the study was to determine the quality of life and health of patients in the long-term period (24 months) after hospitalization for COVID-19-associated pneumonia. Material and methods. The study was conducted on data from 158 patients with moderate and severe severity who were hospitalized during the first wave of coronavirus infection in the period 09/01/2020-11/30/2020. To assess the quality of life in the post-Covid period the VR-12 questionnaire was used. The study involved conducting structural and frequency analysis, assessing the consistency of answers to the questionnaire using Cronbach's alpha and the chi-square test, calculating the nonparametric Spearman rank correlation coefficient, and non-serial correlation coefficients. To identify factors influencing health assessments, a linear regression model was built. Ordered logistic regression was estimated to identify factors influencing the distribution of responses to additional questions. Results. The analysis showed an significant difference between the physical component summary (PCS) and mental component summary (MCS) of the respondents. A connection was found between age and the risk of deterioration in self-esteem of health. It was possible to identify a significant difference in the self-assessment of the quality of physical and mental health in men and women, taking into account adjustment for age, two years after suffering from pneumonia, and also to substantiate the non-significance of RDS during hospitalization, given the significance of a high percentage of lung damage for the lower self-assessment of health of persons who had suffered coronavirus infection of moderate and severe severity. Conclusion. The results are largely consistent with studies conducted in other countries, indicating an uneven change in post-Covid consequences and emphasizing the importance of individual recovery programs taking into account the severity of the disease, age and gender of patients.

About the Authors

I. A. Lakman
Ufa University of Science and Technology
Russian Federation

Lakman Irina Aleksandrovna – PhD, Associate Professor of the Department of Biomedical Engineering, Head of the Scientific Laboratory for the Study of Social and Economic Problems of Regions



V. M. Timiryanova
Ufa University of Science and Technology
Russian Federation

Timiryanova Venera Maratovna – Doctor of Economics, Chief Researcher of the Scientific Laboratory for the Study of Social and Economic Problems of Regions



A. A. Agapitov
Ufa University of Science and Technology
Russian Federation

 Agapitov  Alexander Aleksandrovich – intern-researcher of the department 
of scientific research



L. F. Sadikova
Ufa University of Science and Technology
Russian Federation

Sadikova Liana Floritovna – intern-researcher of the department of scientific research



B. T. Idrisov
Bashkir State Medical University
Russian Federation

Idrisov  Bulat Tagirovich – assistant at the Department of Infectious Diseases



R. I. Sladkov
Ufa University of Science and Technology
Russian Federation

Sladkov Roman Igorevich – graduate student



N. Sh. Zagidullin
Ufa University of Science and Technology; Bashkir State Medical University
Russian Federation

Zagidullin  Naufal Shamilevich – Doctor of Medical Sciences, Leading Researcher of the Research Department; head of the department of propaedeutics of internal diseases



D. F. Gareeva
Ufa University of Science and Technology; Bashkir State Medical University
Russian Federation

Gareeva Diana Firdavisovna – Candidate of Medical Sciences, Senior Researcher of the Department of Scientific Research; associate professor of the department. Department of Propaedeutics of Internal Diseases



References

1. Gulyaev P.V., Resnyanskaya S.V., Ostrovskaya I. V. Detection of post-coronavirus syndrome in patients who have had a new coronavirus infection // Current problems of health care and medical statistics. 2022. Vol. 2. P. 107-125. DOI: 10.24412/2312-2935-2022-2-107-128.

2. Neurological manifestations of long COVID: clinical aspects and impact on quality of life / Skvortsov V.V. [et al.] // Bulletin of Neurology, Psychiatry and Neurosurgery. 2023. Vol.4. P. 264- 269. DOI: 10.33920/med-01-2304-03.

3. 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study / Huang L. [et al.] // Lancet. 2021. Vol. 398(10302). P.747- 758. DOI: 10.1016/S0140-6736(21)01755-4.

4. A clinical case definition of post-COVID-19 condition by a Delphi consensus / Soriano J.B. [et al.] // Lancet Infect Dis. 2022. Vol. 22(4). P. e102-e107. DOI: 10.1016/S1473-3099(21)00703-9.

5. COVID-19 in Health-Care Workers: A Living Systematic Review and Meta-Analysis of Prevalence, Risk Factors, Clinical Characteristics, and Outcomes / Gómez-Ochoa S.A. [et al.] // Am J Epidemiol. 2021. Vol. 190(1). P.161-175. DOI: 10.1093/aje/kwaa191.

6. Effect of COVID-19 on Health-Related Quality of Life in Adolescents and Children: A Systematic Review / Nobari H. [et al.] // Int J Environ Res Public Health. 2021. Vol. 18(9). 4563. DOI: 10.3390/ijerph18094563.

7. Extreme obesity is a strong predictor for in-hospital mortality and the prevalence of longCOVID in severe COVID-19 patients with acute respiratory distress syndrome / Heubner L. [et al.] // Sci Rep. 2022. Vol. 12(1). 18418. DOI: 10.1038/s41598-022-22107-1.

8. Fatigue and cognitive impairment in PostCOVID-19 Syndrome: A systematic review and meta-analysis / Ceban F. [et al.] // Brain Behav Immun. 2022. Vol. 101. P.93-135. DOI: 10.1016/j.bbi.2021.12.020.

9. Frequency, signs and symptoms, and criteria adopted for long COVID-19: A systematic review / Cabrera Martimbianco A.L. [et al.] // Int J Clin Pract. 2021. Vol. 75(10). e14357. DOI: 10.1111/ijcp.14357.

10. Health-related quality of life of COVID-19 two and 12 months after intensive care unit admission / Demoule A. [et al.] // Ann Intensive Care. 2022. Vol. 12(1). 16. DOI: 10.1186/s13613-022-00991-0.

11. Healthy outcomes of patients with COVID-19 two years after the infection: a prospective cohort study / Li D. [et al.] // Emerg Microbes Infect. 2022. Vol. 11(1). P. 2680-2688. DOI: 10.1080/22221751.2022.2133639.

12. Improving the response choices on the veterans SF-36 health survey role functioning scales: results from the Veterans Health Study / Kazis L.E. [et al.] // J Ambulatory Care Manage. 2004. Vol. 27(3). P. 263-280. DOI: 10.1097/00004479-200407000-00010.

13. Insomnia, anxiety, and depression during the COVID-19 pandemic: an international collaborative study / Morin C.M. [et al.] // Sleep Med. 2021. Vol. 87. P. 38-45. DOI: 10.1016/j.sleep.2021.07.035.

14. Investigation of hs-TnI and sST-2 as Potential Predictors of Long-Term Cardiovascular Risk in Patients with Survived Hospitalization for COVID-19 Pneumonia / Fiedler L. [et al.] // Biomedicines. 2022. Vol. 10(11). 2889. DOI: 10.3390/biomedicines10112889.

15. Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus / Raman B. [et al.] // Eur Heart J. 2022. Vol. 43(11). P. 1157- 1172. DOI: 10.1093/eurheartj/ehac031

16. Longitudinal Clinical Features of PostCOVID-19 Patients-Symptoms, Fatigue and Physical Function at 3- and 6-Month Follow-Up / Steinmetz A. [et al.] // J Clin Med. 2023. Vol. 12(12). 3966. DOI: 10.3390/jcm12123966.

17. Longitudinal course and predictors of health-related quality of life, mental health, and fatigue, in non-hospitalized individuals with or without post COVID-19 syndrome / Kirchberger L. [et al.] // Health and Quality of Life Outcomes. 2023. Preprint. DOI: 10.21203/rs.3.rs-3221088/v1.

18. Long-term cardiovascular outcomes of COVID-19 / Xie Y. [et al.] // Nat Med. 2022. Vol. 28(3). P. 583-590. DOI: 10.1038/s41591-022-01689-3.

19. Long-Term Impacts of COVID-19 Pneumonia on Quality of Life: A Single Institutional Pilot Study / Deesomchok A. [et al.] // Healthcare (Basel). 2023. Vol. 11(13). 1963. DOI: 10.3390/healthcare11131963.

20. Neurological manifestations of longCOVID syndrome: a narrative review / Stefanou M.I. [et al.] // Ther Adv Chronic Dis. 2022. Vol. 13. 20406223221076890. DOI: 10.1177/20406223221076890.

21. Post COVID Rehabilitation Study and Research (PoCoRe)-Study Design, Characteristics and Evaluation Tools / Steinmetz A. [et al.] // J Clin Med. 2023. Vol. 12(2). 624. DOI: 10.3390/jcm12020624.

22. Quality of Life and Mental Health Status in Recovered COVID-19 Subjects at Two Years after Infection in Taizhou, China: A Longitudinal Cohort Study / Pan J. [et al.] // Brain Sci. 2022. Vol. 12(7). 939. DOI: 10.3390/brainsci12070939.

23. Sex differences in sequelae from COVID-19 infection and in long COVID syndrome: a review / Sylvester S.V. [et al.] // Curr Med Res Opin. 2022. Vol. 38(8). P. 1391-1399. DOI: 10.1080/03007995.2022.2081454

24. Sex-differences in the longitudinal recovery of neuromuscular function in COVID-19 associated acute respiratory distress syndrome survivors / Lulic-Kuryllo T. [et al.] // Front Med (Lausanne). 2023. Vol. 10. 1185479. DOI: 10.3389/fmed.2023.1185479

25. Two-Year Health Outcomes in Hospitalized COVID-19 Survivors in China / Yang X. [et al.] // JAMA Netw Open. 2022. Vol. 5(9). e2231790. DOI: 10.1001/jamanetworkopen.2022.31790.

26. Two-year physical, mental and cognitive outcomes among intensive care unit survivors treated for COVID-19 / Heesakkers H. [et al.] // Intensive Care Med. 2023. Vol. 49(5). P. 597-599. DOI: 10.1007/s00134-023-07038-3.


Review

For citations:


Lakman I.A., Timiryanova V.M., Agapitov A.A., Sadikova L.F., Idrisov B.T., Sladkov R.I., Zagidullin N.Sh., Gareeva D.F. Quality of health of hospitalized COVID-19 patients in the post-COVID period: a two-year follow-up. Yakut Medical Journal. 2023;(4):82-88. https://doi.org/10.25789/YMJ.2023.84.20

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)