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Content of hormones in the population of South Yakutia working in an area with natural radiation

https://doi.org/10.25789/YMJ.2023.84.16

Abstract

A study of the level of hormones in the blood serum was carried out in 173 residents of the Aldan region aged from 22 to 75 years, of which 65 (39.8%) were men and 108 (60.2%) women, the average age was 44.0 (35. 0; 52.0) years. In the working population, there is functional tension of the pituitary-thyroid link, characterized by a higher frequency of occurrence of thyroid hormone levels below the normal T3total. in 27.2%, T3f. in 19.3% and T4f. in 11.6% of people, more pronounced in women. Increased concentrations of thyroid hormones T3f., T4f. and T4tot. observed with age, T3total and T4total in people with an increased body mass index. The presence of increased levels of antibodies to thyroid peroxidase in 18 (10.4%) people indicates a strained immune system, therefore it is recommended to include endocrinological examinations in periodic medical examinations.

About the Authors

E. D. Okhlopkova
Federal State Budgetary Institution Yakut Scientific Center of Complex Medical Problems
Russian Federation

Okhlopkova Elena Dmitrievna – Ph.D. in Biology , senior researcher



L. I. Konstantinova
Federal State Budgetary Institution Yakut Scientific Center of Complex Medical Problems
Russian Federation

Konstantinova Lena Ivanovna – Ph.D. in Biology, research fellow



A. A. Grigorieva
Federal State Budgetary Institution Yakut Scientific Center of Complex Medical Problems
Russian Federation

Grigorieva Anastasia Anatolyevna – junior researcher 



S. D. Efremova
Federal State Budgetary Institution Yakut Scientific Center of Complex Medical Problems
Russian Federation

Efremova Svetlana Dmitrievna – junior researcher 



L. D. Olesova
Federal State Budgetary Institution Yakut Scientific Center of Complex Medical Problems
Russian Federation

Olesova Lyubov Dygynovna – Ph.D. in Biology, senior research scientist-supervisor. lab.



A. I. Yakovleva
Federal State Budgetary Institution Yakut Scientific Center of Complex Medical Problems
Russian Federation

Yakovleva  Alexandra Ivanovna – research fellow 



S. I. Sofronova
Federal State Budgetary Institution Yakut Scientific Center of Complex Medical Problems
Russian Federation

Sofronova  Sargylana Ivanovna – Ph.D., chief researcher, head of the science division 



T. E. Popova
Federal State Budgetary Institution Yakut Scientific Center of Complex Medical Problems
Russian Federation

Popova  Tatyana Egorovna – MD, Deputy Director of Research



A. N. Romanova
Federal State Budgetary Institution Yakut Scientific Center of Complex Medical Problems
Russian Federation

Romanova  Anna Nikolaevna – MD, Director



References

1. Analysis of the results of the latest epidemiological studies of the influence of radon on morbidity and mortality of the population / A.R. Tukov [et al.] // Medicine of extreme situations. 2012. https://cyberleninka.ru/article/n/analiz-rezultatov-noveyshih-epidemiologicheskih-issledovaniy-vliyaniya-radona-na-zabolevaemost-i-smertnost-naseleniya/viewer

2. Biryukova E.V. Hypothyroidism: current state of the problem. Medical Council. 2020. No. 7. P. 96–107. doi: 10.21518/2079-701X-2020-7-96-107

3. Buivalenko U.V., Levshina A.R., Sakhnova E.E. Laboratory biomarkers of differentiated thyroid cancer // Clinical and experimental thyroidology. 2022. No. 18(1) P.21-28. https://doi.org/10.14341/ket12715

4. Demin D.B. Effects of thyroid hormones in the development of the nervous system (review) / D.B. Demin // Journal of medical and biological research. 2018. T. 6, no. 2. pp. 115-127. DOI: 10.17238/issn2542-1298.2018.6.2.115

5. Efremova M. In the Aldan region there are places with increased radiation // Yakutsk evening. 2022. December 5. https://vecherniy.com/news/v_aldanskom_rajone_imejutsja_mesta_s_povyshennoj_radiaciej/2022-12-05-983

6. Study and assessment of the characteristics of the course of thyroid pathology among the population of the southern regions of the East Kazakhstan region, exposed to irradiation during nuclear weapons testing / A.E. Izatova, E.M. [et. al.]// International Journal of Applied and Fundamental Research. 2017. No. 2(2). P. 190- 192 URL: https://applied-research.ru/ru/article/view?id=11243 (дата обращения: 17.10.2023).

7. Iodine and the health of the population of Siberia / M.F. Savchenko [et al.] - Novosibirsk, 2002. 287p.

8. Kazachenok N.N. Radioecological problems in the zone of radioactive contamination. Mogilev: Belarusian-Russian. univ., 2020. 309 p.

9. Kubasov R.V. Hormonal changes in response to extreme environmental factors / R.V. Kubasov // Bulletin of the Russian Academy of Medical Sciences. 2014. No. 9(10). P.102-109.

10. Koryagin A.S. Fundamentals of endocrinology // Educational manual. – Nizhny Novgorod, 2016. 109 p.

11. National clinical guidelines for the treatment of morbid obesity in adults. 3rd revision / I.I. Dedov [et al.] // Obesity and metabolism. 2018; 15(1): 53-70.

12. Fundamentals of environmental safety (radionuclides and heavy metals) in the Aldan region of the Sakha Republic (Yakutia) / A.P. Chevychelov [et al.] Materials of the II All-Russian scientific and practical conference dedicated to the 100th anniversary of the Yakut Autonomous Soviet Socialist Republic (YASSR) “Geography and local history in Yakutia and adjacent territories of Siberia and the Far East.” Yakutsk, March 25–26, 2022, P. 114-119.

13. Program for the socio-economic development of the Municipal Entity “Aldan District” for years. – 2007. https://pandia.ru/text/78/198/47785-29.php

14. Radiation situation of the RSE territory of the Republic of Sakha (Yakutia) for 2021. https://minpriroda.sakha.gov.ru/uploads/ckfinder/userfiles/2022/06/09/files/РГП%20территории%20РС(Я)%20за%202021%20г.pdf

15. Khasnulin V.I. Psycho-emotional manifestations of northern stress and the state of immunity among newcomers to the north // Human Ecology. 2011. No.12. P.3-7. https://cyberleninka.ru/article/n/psihoemotsionalnye-proyavleniya-severnogo-stressa-i-sostoyanie-immuniteta-u-prishlyh-zhiteley-severa/viewer

16. Maslovskaya, A.A. Biochemistry of hormones: a manual for students of pediatric, medical-psychological, medical-diagnostic faculties and the faculty of foreign students / A.A. Maslovskaya. – 6th ed. Grodno: Grodno State Medical University, 2012. 44 p.

17. Endocrine disorders and changes in bone mineral density in workers of the Severomuysk tunnel under conditions of prolonged exposure to radon / E. V. Katamanova, [et al.] // Human Ecology. 2013. No. 12. P.40-43.

18. Higher serum thyroid stimulating hormone level in thyroid nodule patients is associated with greater risks of differentiated thyroid cancerand advanced tumor stage / M.R. Haymart [et al.] // J Clin Endocrinol Metab. 2008;93(3):809-814. https://doi.org/10.1210/jc.2007-2215.


Review

For citations:


Okhlopkova E.D., Konstantinova L.I., Grigorieva A.A., Efremova S.D., Olesova L.D., Yakovleva A.I., Sofronova S.I., Popova T.E., Romanova A.N. Content of hormones in the population of South Yakutia working in an area with natural radiation. Yakut Medical Journal. 2023;(4):63-68. https://doi.org/10.25789/YMJ.2023.84.16

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)