In-vitro evaluation of the antioxidant activity of aqueous and ethanol extracts of VACCINIUM VITIS-IDAEAE L.
https://doi.org/10.25789/YMJ.2024.85.06
Abstract
Biologically active substances in lingonberry leaves (Vaccinium vitis-idaeae L.) have antioxidant properties. This study selected the optimal extraction method to obtain extracts with a high content of biologically active components with antioxidant activity from the leaves of Vaccinium vitis-idaeae growing in Yakutia. The data obtained allow us to conclude that biologically active substances isolated by alcoholic extraction from the leaves of Vaccinium vitis-idaeae can be used in medicine to find approaches to regulating pro-oxidant processes in the human body under various pathological conditions.
About the Authors
E. V. TomtosovaRussian Federation
TOMTOSOVA Eugenia Viktorovna – junior researcher, Epidemiology of Chronic Non-Infectious Diseases Department
E. K. Rumyantsev
Russian Federation
RUMYANTSEV Egor Konstantinovich – junior researcher, Arctic Medical Center
V. M. Nikolaev
Russian Federation
NIKOLAEV Vyacheslav Mikhailovich – PhD in Biology, senior researcher, Epidemiology of Chronic Non-Infectious Diseases Department
N. K. Chirikova
Russian Federation
CHIRIKOVA Nadezhda Konstantinovna – Doctor of Pharmacy, Professor, Biological Department
References
1. Borisova N.I., Timofeev P.A. Zapasy listyev brusniki v lesakh Yakutii. Tezisy dokladov konferentsii II(X) sezdu Russkogo botanicheskogo obshchestva «Problemy botaniki na rubezhe XX-XXI vekov» [Stocks of lingonberry leaves in the forests of Yakutia // Abstracts of reports of the conference II (X) Congress of the Russian Botanical Society 'Issues of botany at the turn of the XX-XXI centuries' 1. St. Petersburg, 333. 1988 (In Russ.).]
2. Klebanov G.I. [et al.] Otsenka antiokislitelnoy aktivnosti plazmy krovi s primeneniem zheltochnykh lipoproteidov [ [Assessment of the antioxidant activity of blood plasma using yolk lipoproteins]. Laboratornoe delo [Laboratory Science.1988; 5: 59-62 (In Russ.).]
3. Raudone L. [et al.]. Antioxidant Activities of Vaccinium vitis-idaea L. Leaves within Cultivars and Their Phenolic Compounds. Molecules. 2019; 24(5):844. .https://doi.org/10.3390/molecules24050844
4. Ștefănescu B.E. [et al.]. Chemical Composition and Biological Activities of the Nord-West Romanian Wild Bilberry (Vaccinium myrtillus L.) and Lingonberry (Vaccinium vitis-idaea L.) Leaves. Antioxidants. 2020; 9(6): 495. https://doi.org/10.3390/antiox9060495
5. Xu J. [et al.]. Comprehensive phytochemical analysis of lingonberry (Vaccinium vitis-idaea L.) from different regions of China and their potential antioxidant and antiproliferative activities. RSC advances. 2023; 13(42): 29438–29449. https://doi.org/10.1039/d3ra05698h
6. Zargoosh Z. [et al.]. Effects of ecological factors on the antioxidant potential and total phenol content of Scrophularia striata Boiss. Sci. Rep. 2019; 9: 16021.https://doi.org/10.1038/s41598-019-52605-8
7. Inhibitory effects of lingonberry (Vaccinium vitis-idaea L.) fruit extract on obesity-induced inflammation in 3T3-L1 adipocytes and RAW 264.7 macrophages / Kowalska K. [et al.] // English. Journal of Functional Foods. 2019; 54: 371–380, https://doi.org/10.1016/j.jff.2019.01.040
8. Reichert K.P. [et al.]. Lingonberry Extract Provides Neuroprotection by Regulating the Purinergic System and Reducing Oxidative Stress in Diabetic Rats. Molecular nutrition & food research 62(16), e1800050. 2018. https://doi.org/10.1002/mnfr.201800050
9. Urbonaviciene D. [et al.]. Nutritional and Physicochemical Properties of Wild Lingonberry (Vaccinium vitis-idaea L.) Effects of Geographic Origin. Molecules. 2023; 28: 4589. https://doi.org/10.3390/molecules28124589
10. Bujor O. [et al.]. Phenolic compounds and antioxidant activity of lingonberry (Vaccinium vitis-idaea L.) leaf, stem and fruit at different harvest periods. Food chemistry. 2018; 252: 356–365. https://doi.org/10.1016/j.foodchem.2018.01.052
11. Vilkickyte G., Raudone L., Petrikaite V. Phenolic Fractions from Vaccinium vitis-idaea L. and Their Antioxidant and Anticancer Activities Assessment/ Antioxidants. 2020; 9(12): 1261. https://doi.org/10.3390/antiox9121261
Review
For citations:
Tomtosova E.V., Rumyantsev E.K., Nikolaev V.M., Chirikova N.K. In-vitro evaluation of the antioxidant activity of aqueous and ethanol extracts of VACCINIUM VITIS-IDAEAE L. Yakut Medical Journal. 2024;(1):24-26. https://doi.org/10.25789/YMJ.2024.85.06