Some features of the microbiota composition of Wickham’s striae surface and erosive- ulcerative elements in patients with oral lichen planus

   A comparative study of the microbiota profile of the Wickham mesh surfaces (a typical form of lichen planus (LP) (L43.80) and erosive-ulcerative elements in the erosive-ulcerative form (L43.82) of LP with localization on the buccal mucosa was carried out. In the studied microbiota of the surface of erosive and ulcerative elements, significant differences were revealed from the composition of the microbiota of the surface of the Wickham mesh, which is associated with clinical manifestations of the oral cavity mucous lining (LP OCML). The data on the quantitative and qualitative composition of microorganisms in the erosive-ulcerative form of LP were significantly different from the typical form of LP, which indicates the need for further studies of the microbiota in other forms of LP OCML. The revealed changes in the composition of the microbiota in the typical form of LP OCML can serve as a potential prognostic criterion for the conditional norm, and in the erosive-ulcerative form, as a criterion indicating the progression and aggravation of the clinical picture.

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