Preview

Yakut Medical Journal

Advanced search

Peripheral blood cellular immunity parameters in COVID-19

https://doi.org/10.25789/YMJ.2022.80.18

Abstract

This article carried material about the results of the investigation of peripheral blood cellular immunity parameters in the COVID-19 patients with ≤30% lung damage hospitalizated in 2020 year. When infected with SARS-CoV-2 on the background of severe lymphopenia and neutrophilia were revealed the multidirectional changing in a cellular immunity parameters, the severity and dynamics of which can be determined by the initial type of immune system response

About the Authors

Zh. P. Vasneva
Samara Diagnostic Center; Samara National Research University
Russian Federation

Vasneva Zhanna P. – PhD, laboratory assistant, Samara Diagnostic Center; Associate Professor of the Department of Laser and Biotechnical Systems of the Samara National Research University



E. A. Borodulina
Samara State Medical University of the Ministry of Health of Russia
Russian Federation

Borodulina Elena A. – MD, Professor, head of the Department of Phthisiology and Pulmonology



B. E. Borodulin
Samara State Medical University of the Ministry of Health of Russia
Russian Federation

Borodulin Boris E. – MD, Professor of the Department of Phthisiology and Pulmonology,



E. S. Vdoushkina
Samara State Medical University of the Ministry of Health of Russia
Russian Federation

Vdoushkina Elizaveta S. – Candidate of Medical Sciences, Associate Professor of the Department of Phthisiology and Pulmonology



A. E. Sukhanova
Samara State Medical University of the Ministry of Health of Russia
Russian Federation

Sukhanova Anna E. – resident of the Department of Phthisiology and Pulmonology



References

1. Abdullaev R.YU., Komissarova O.G. Laboratornye proyavleniya koronavirusnoj infekcii COVID-19 [Laboratory manifestations of coronavirus infection]. Vrach (The Doctor). 2020; 31(5):3-5 (In Russ.).]

2. Vdoushkina E.S., Borodulina E.A., Povalyaeva L.V., Sukhanova A.V., Zhilinskaya K.V., Sutyagin A.V. Sroki obrashcheniya i tyazhest' sostoyaniya pacientov s porazheniem legkih i podozreniem na novuyu koronavirusnuyu infekciyu pri postuplenii v stacionar v period nachala pandemii [Terms of treatment and severity of the condition of patients with lung damage and suspected new coronavirus infection upon admission to the hospital during the onset of the pandemic]. Vrach (The Doctor). 2020:31(11):60-63 (In Russ.).]

3. Sizyakina L.P., Zakurskaya V.Ya., Skripkina N.A., Antonova E.A. Uroven' ferritina kak prediktor tyazhelogo techeniya COVID-19. Immunologiya [Immunology. 2021;42(5):518-25 (In Russ.).]

4. Baazim H., Schweiger M, Moschinger M. [et al.] CD8+ T cells induce cachexia during chronic viral infection. Nat Immunol. 2019; 20 (6): 701710.

5. Chen G., Wu D., Guo W [et al.] Clinical and immunological features of severe and moderate coronavirus disease 2019. Clin.Invest. 2020; 130 (5): 2620–2629.

6. Golovkin A., Kalinina O., Bezrukikh V. [et al.] Imbalanced immune response of T – cell and B – cell subsets in patients with moderate and severe COVID-19. Viruses. 2021; 13: 1966.

7. Guan W., Ni Z., Hu Y. [et al.] Clinical Characteristics of Coronavirus Disease 2019 in China. Engl. J. Med. 2020; 382 (18): 1708-1720.

8. Li G., Fan Y, Lai Y [et al.] Coronavirus infections and immune responses. J. Med. Virol. 2020; 92 (4): 424–32.

9. Li Y.X., Wu W., Yang T. [et al.] Characteristics of peripheral blood leukocyte differential counts in patients with COVID-19. Chinese Medical Association Publishing House Ltd. 2020; 59 (5): 372-374.

10. Qin C., Zhou L., Hu Z. [et al.] Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect Dis. 2020; 71 (15): 762-768.

11. Ruan Q., Yang K., Wang W. [et al.] Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan. China Intensive CareMed. 2020; 46 (6):12941297.

12. Saghazadeh A, Rezaei N. Immune-epidemiological parameters of the novel coronavirus – a perspective. Expert Rev. Clin. Immunol. 2020; 16 (5): 465-470


Review

For citations:


Vasneva Zh.P., Borodulina E.A., Borodulin B.E., Vdoushkina E.S., Sukhanova A.E. Peripheral blood cellular immunity parameters in COVID-19. Yakut Medical Journal. 2022;(4):68-70. https://doi.org/10.25789/YMJ.2022.80.18

Views: 26


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)