Parkinson disease and ischemic stroke (clinical case)
https://doi.org/10.25789/YMJ.2023.81.33
Abstract
Parkinson's disease (PD) – is a chronic neurodegenerative disease that ranks 2nd in prevalence in the world and has a steadily progressive course. It is clinically manifested by motor disorders in the form of hypokinesia, muscle rigidity and/or rest tremor. In addition, patients have non-motor symptoms, some of which may occur long before the development of typical motor manifestations. Cerebrovascular diseases are in the first place in terms of mortality and disability. A number of studies have revealed that PD reduces vascular risk factors due to low activity of the sympathetic part of the autonomic nervous system, disorders of the hypothalamic-pituitary-adrenal axis, as well as due to treatment with dopaminergic drugs. Contradictory results are expressed by a number of other authors, according to which PD is associated, on the contrary, with an increase in the risk of stroke. This article presents a clinical case of a patient with an established diagnosis of PD who has developed an ischemic stroke. The possible mechanisms of the combination of two diseases, the influence of the neurodegenerative process on the recovery processes and the timing of hospitalization are discussed.
About the Authors
L. I. Кopylova
Medical Institute, M. K. Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
Kopylova Liliya I. – Assistant of the Department of Neurology and Psychiatry; post-graduate student of 2 years of study
T. Ya. Nikolaeva
Medical Institute, M.K. Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
Nikolaeva Tatiana Ya. – MD, Professor, Head of the Department of Neurology and Psychiatry
A. A. Tappakhov
Medical Institute, M.K. Ammosov North-Eastern Federal University; Yakut Scientific Center for Complex Medical Problems
Russian Federation
Russian Federation
Tappakhov Alexey A. – Candidate of Sciences in Medicine, Associate Professor at the Department of Neurology and Psychiatry; Senior Researcher
Yakutsk
Yu. E. Semenova,
Republican Hospital № 2-TSEMP
Russian Federation
Russian Federation
Semenova Yulia E. – neurologist
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Review
For citations:
Кopylova L.I., Nikolaeva T.Ya., Tappakhov A.A., Semenova, Yu.E. Parkinson disease and ischemic stroke (clinical case). Yakut Medical Journal. 2023;(1):130-133. https://doi.org/10.25789/YMJ.2023.81.33
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