Clinical-endoscopic characteristic of diseases of the esophagus and stomach, associated with Helicobacter pylori, in various ethnic groups of the patients, constantly living in conditions of the North

Abstract

The purpose of the present work was studying of clinical-endoscopic manifestations of gastroesophageal reflux disease (GERD), chronic gastritis (ChG) with dyspepsia, ulcerative disease of the stomach (UDS) in various ethnic groups of patients.
371 patients have been included in research, from them 183 – of the Asian ethnicity (1st group) and 188 – European (2nd group). Esophagog astroduodenoscopy was carried out to patients with taking biopsy materials from esophagus lower third, body and antral portion of a stomach. For research on Helicobacter pylori histological, immunological and biochemical methods were used.
Conclusion. In clinical manifestations and current of GERD, ChG and UDS Asian and European ethnic groups have a number of distinctive features. In patients of the Asian group intensity of a painful syndrome is essentially lower, frequency of atrophic changes of a mucous membrane of stomach is considerably higher, than in the European. At morphological research in the 1-st group the light degree of activity and a low degree of НР-seeding of a mucous membrane of stomach also prevailed.