Antibacterial properties of cephotaxim, mechanically immobilized on the polymeric carrier
Abstract
Comparative studying of antibacterial activity of mechanically modified complex connection representing a mix of 3d generation cephalosporin -cephotaxim and dextran with various molecular mass is conducted. It is revealed that, native and mechanically modified dextran of various molecular mass does not possess antibacterial activity. Mechanochemical cephotaxim updating with dextran leads to increase in antibacterial properties of the given antibiotic concerning Staphylococcus aureus and Escherichia coli.
About the Authors
K. V. Gajdul
ГУ НИИКИ СО РАМН
Russian Federation
Russian Federation
I. A. Goldina
ГУ НИИКИ СО РАМН
Russian Federation
Russian Federation
I. V. Safronova
ГУ НИИКИ СО РАМН
Russian Federation
Russian Federation
J. L. Jakimova
МСЧ № 68
Russian Federation
Russian Federation
V. A. Kozlov
ГУ НИИКИ СО РАМН
Russian Federation
Russian Federation
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Review
For citations:
Gajdul K.V., Goldina I.A., Safronova I.V., Jakimova J.L., Kozlov V.A. Antibacterial properties of cephotaxim, mechanically immobilized on the polymeric carrier. Yakut Medical Journal. 2009;(2):163-164. (In Russ.)
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