Preimplantation DNA-diagnostics for single gene disorders
Abstract
Preimplantation genetic diagnosis (PGD) provides an opportunity to prevent single gene disorders at the earliest stages of human embryo development. Despite complications of tHis diagnosis, including the necessity of IVF (in vitro fertilization) for partners, limited time for analysis performing and minimum DNA quantity, PGD technique is developing very fast and becoming a part of clinical practice. One of the main problems to solve for DNA analysis of single cells is effective amplification of genetic material.
About the Authors
E. V. Markova
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
O. M. Kazantseva
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
V. G. Artjuhova
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
A. V. Svetlakov
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
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Review
For citations:
Markova E.V., Kazantseva O.M., Artjuhova V.G., Svetlakov A.V. Preimplantation DNA-diagnostics for single gene disorders. Yakut Medical Journal. 2009;(2):72-74. (In Russ.)
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