Genetic factors of obesity
https://doi.org/10.25789/YMJ.2023.82.24
Abstract
The review describes the genetic causes of obesity, including syndromal, monogenic and polygenic causes. The rapidly increasing prevalence of obesity in the population in recent decades is an important public health issue because it increases the risk of diabetes, heart disease, stroke and other serious diseases. Its causes include excessive consumption of high-calorie foods, as well as a sedentary lifestyle. It has been proven that, in addition to energy imbalance, 40–70 % of the development of obesity is influenced by hereditary factors. As a rule, obesity results from the interaction of certain gene polymorphisms with the environment. Only a small number of cases of obesity are the result of the presence of mutations in certain genes (monogenic obesity), causing Mendelian syndromes with a very low frequency in the population.
About the Authors
N. I. Pavlova
Yakut Scientific Center for Complex Medical Problems
Russian Federation
Russian Federation
Yakutsk
V. A. Alekseev
Arctic Medical Center
Russian Federation
Russian Federation
Yakutsk
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Review
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Pavlova N.I., Alekseev V.A. Genetic factors of obesity. Yakut Medical Journal. 2023;(2):102-106. https://doi.org/10.25789/YMJ.2023.82.24
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