Preview

Yakut Medical Journal

Advanced search

Structurally functional condition of erythrocyte membranes in newborns at anemia of pregnant women

Abstract

In order to study the molecular organization of erythrocyte membranes of umbilical cord blood of newborns by the method of fluorescence sensing erythrocytes of umbilical cord blood of 37 newborns from mothers with iron deficiency anemia (IDA) (main group) and 34 newborns from mothers with normal hemoglobin (control group) were investigated. It was revealed that for the state of erythrocyte membranes in neonates at the iron deficiency anemia in pregnant women the transformation of its protein component and a decrease in calcium-accumulating function is characteristic. The authors assume that the conformation of the protein component of erythrocyte membrane may be due to changes caused by deficient erythropoiesis of fetus at the anemia in pregnant women, which affects the major functions of erythrocyte membrane.

About the Authors

J. H. Davaa
НИИ медицинских проблем Севера СО РАМН
Russian Federation


M. V. Shubina
НИИ медицинских проблем Севера СО РАМН
Russian Federation


O. I. Zajtseva
НИИ медицинских проблем Севера СО РАМН
Russian Federation


S. J. Tereshchenko
НИИ медицинских проблем Севера СО РАМН
Russian Federation


References

1. Vladimirov Y.A. Fluorescent probes in the study of biological membranes / Y.A. Vladimirov, G.E. Dobretsov. - M.: Nauka, 1980. - 320 p.

2. Pakhmutova O.A. Clinical and structural - functional organization of erythrocyte membranes at latent iron deficiency among adolescent girls and young women: abstract. dis. ... cand. med.science / O.A.Pahmutova. - Krasnoyarsk, 2008. - P. 24.

3. Preobraghenskiy D.V. Consilium Medicum. Women’s Health / D.V. Preobraghenskiy, I.D. Vyshinskaya / / Consilium Medicum. -2008. - V.10, № 6. - P. 12-16.

4. Allen L. H. Anemia and iron deficiency: effects on pregnancy outcome / L.H. Allen // Am J Clin Nutr. – 2000. – Vol. 71, № 5 Suppl. – P. 1280S-1284S.

5. Allen L. H. Biological mechanisms that might underlie iron’s effects on fetal growth and preterm birth / L.H. Allen // J Nutr. – 2001. – Vol. 131, № 2S-2. – P. 581S-589S.

6. Maternal and fetal outcome after severe anemia in pregnancy in rural Ghana / D. Geelhoed [et al] // Acta Obstet Gynecol Scand. – 2006. – Vol. 85, № 1. – P. 49-55.

7. The preparation and hemical characteristics of hemoglobin - free shosts of human erythrocyts / J.T. Dodge, C. Mitchell, D. Hanahan // Arch.Biochem. and Biophis. – 1980. – Vol. 100, № 1. – P. 119-130.

8. Status of vitamin A, vitamin B2, iron and an-oxidantive activity in anemic pregnant women in China / F. Yang [et al] // Wei Sheng Yan Jiu. – 2006. – Vol. 35, № 3. – P. 320-322.


Review

For citations:


Davaa J.H., Shubina M.V., Zajtseva O.I., Tereshchenko S.J. Structurally functional condition of erythrocyte membranes in newborns at anemia of pregnant women. Yakut Medical Journal. 2010;(2):9-11. (In Russ.)

Views: 6


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)