Preview

Yakut Medical Journal

Advanced search

Molecular interactions of liposoluble vitamins (retinol and alpha tocopherol) with parameters of a functional state of erythrocytic membranes in Evenkia children

Abstract

In healthy children of the indigenous and non-indigenous population of Evenkia from 1 to 3 years the structural and functional properties of erythrocyte membranes with definition of lipid profile, levels of lipo-soluble vitamins (retinol and alpha-tocopherol) were studied. Physical and chemical properties of erythrocyte membranes: indices of mobility of molecules in the surface and in the hydrocarbon regions, the level of structured water and the degree of optical lability were established. By the method of pair correlation relationships it was found that liposoluble vitamins (retinol and alpha-tocopherol) displayed ambiguous functional properties to the molecular structure of erythrocyte membranes in children of different ethnicity.

About the Authors

T. A. Kolodjazhnaja
SRI of the medical problems of the North SD RAMS
Russian Federation

Krasnoyarsk city



O. I. Zajtseva
SRI of the medical problems of the North SD RAMS
Russian Federation

Krasnoyarsk city



V. I. Manchuk
SRI of the medical problems of the North SD RAMS
Russian Federation

Krasnoyarsk city



G. N. Kazakova
Krasnoyarsk State Medical University named after prof. V.F. Voino-Yasenetsky
Russian Federation


References

1. Bichkaeva F.A. Physiological characteristics of lipid, carbohydrate and protein metabolism in inhabitants of the southern district of the Arkhangelsk Region / F.A. Bichkaeva, E.R. Boyko, O. S. Vlasova, L.P. Zhilina / Human Ecology. − 2006. − № 3. − P.7-11.

2. Boldyrev A.A. Biomembranology: textbook / A.A. Boldyrev, E.I. Kaivyaryaynen, V.A. Elyuha.- Petrozavodsk: Pub. House Kar SC RAS.-2006. - 226 p.

3. Vladimirov Ju.A. Fluorescent probes in the study of biological membranes / Ju.A. Vladimirov, G.E. Dobretsov. - M.: Nauka. − 1980. – 320 p.

4. Kapralov A.A. Physico-chemical properties and biological role of alpha-tocopherol binding proteins / A.A. Kapralov, G.V. Petrova, G.V. Donchenko // Usp .sovr.biol.− 1993. − V. 113 . −Ed.3 . − p. 313-326.

5. Manchuk V.T. State and the formation of the health of small in numbers people of the North and Siberia / V.T. Manchuk, L.A. Nadtochiy. − Krasnoyarsk, 2008.− 179 p.

6. Novitskiy V.V. Physiology and pathophysiology of the erythrocyte / V. V. Novitsky, N. V. Ryazantseva, E.A Stepovaya. − Tomsk: Pub. Tom. University. − 2004. − 202 p.

7. Prakhin E. I. Medical and social aspects of child growth and development in the North / E. I. Prakhin // Materials of the Final Scientific Conference Medical Research Institute for Northern Problems of Medical Sciences. − 2002. Vol. 2 “Issues of preservation and development of public health of the North and Siberia” October 1-2, 2003, Krasnoyarsk . − p. 118-122.

8. Rebrova O. Ju. Statistical analysis of medical data. Note the application package «STATISTICA» / O.Ju. Rebrova. − M.: Media Sphere . − 2002 .− 305 p.

9. Rostovtsev V.N. Quantitative determination of lipid fractions of blood plasma / V.N. Rostovtsev, G. E. Reznik / / Lab. delo. − 1982. − № 4.− P. 26-29.

10. Spirichev V.B. Biological role of fat-soluble vitamins (review) / V.B. Spirichev, I.Y. Kon // VINITI. The Results of science and technology. A series on human and animal physiology. − 1989. − T. 37. – 223 p.

11. Chernyauskene R. Ch. Simultaneous fluorimetric determination of the concentration of vitamin “E” and “A” in the blood serum / R.Ch. Chernyauskene, Z.Z. Varnekyavichene, P.S. Grybauskas / Lab delo . − 1884 . − № 6. − 362-365 p.

12. Yakubova R.R. The method for evaluating the destabilization of membranes of the erythrocytes / R.R. Yakubova, A.V. Murin / Lab. delo . − 1990. − № 5. − p. 26-29.


Review

For citations:


Kolodjazhnaja T.A., Zajtseva O.I., Manchuk V.I., Kazakova G.N. Molecular interactions of liposoluble vitamins (retinol and alpha tocopherol) with parameters of a functional state of erythrocytic membranes in Evenkia children. Yakut Medical Journal. 2011;(4):13-15.

Views: 22


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)