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Lipoprotein lipase - the important genetic factor of 2 type diabetes development in the native population of Yakutia

Abstract

High association of gene LPL, Int8 SNP (rs320) with 2 type diabetes let us possible to make out proposition about mechanism and role of LPL in 2 type diabetes developing.

About the Authors

V. L. Osakovsky
Health Institute
Russian Federation


M. N. Jakovleva
Health Institute
Russian Federation


References

1. Osakovskiy V.L. Metabolic syndrome in the aboriginal population of Yakutia / V.l. Osakovskiy // Yakut medical journal. – 2010. – 2:98-102

2. Anders H. Berg. Reviews: Adipose tissue, inflammation and cardiovascular disease / H. Berg Anders, Philipp E. Scherer //Circulation research – 2005.- 96-C.939-949

3. Charles A. Immunobiology / A.Charles, Jr. Janeway, P. Travers //Garland Publishing Inc. New York and London. – 1994.- 8.8,8.9.

4. Stryer L. Biochemistry: third Edition / L. Stryer. -1988.- Сharter 23.- P. 547-574.

5. Tornvall P. Lipoprotein lipase mass and activity in plasma and their increase after heparin are separate parameters with different relations to plasma lipoproteins/ P. Tornvall, G. Olivecrona, F.Karpe [et al.] //Atherosclerosis, Thrombosis and vascular biology. – 1995.- 15.- P.1086-1093.

6. Wang H. Lipoprotein lipase: from gene to obesity/ H .Wang, R.H. Eckel // Am. J. Physiol. Endoocrinol. Metab. – 2009 -297 (2) - P.E271-88

7. Xin T. A study of lipoprotein lipase gene intron 8 polymorphism in Chinese Han race essential hypertension patients/ T. Xin, T. Jinwen, W. Xiuying [et al.] //Cardiology- 2005.- v.99 (2). –P.263-267.

8. Yoon S. Ch. Association of lipoprotein lipase (LPL) single nucleotide polymorphisms with type 2 diabetes mellitus / S. Ch. Yoon, J. G. Min, R. H. Hye [et al.] //Experimental and molecular medicine – 2008- v.40 (5) – P.523-532


Review

For citations:


Osakovsky V.L., Jakovleva M.N. Lipoprotein lipase - the important genetic factor of 2 type diabetes development in the native population of Yakutia. Yakut Medical Journal. 2011;(3):29-30.

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)