Influence of local anesthetics on dynamics of IL-1 β and IL-2 content in persons of elderly and senile age in the conditions of the prolonged spinal anesthesia
Abstract
It is noticed in article that with ropivacain use on the operation beginning the highest level of proinflammatory IL-1β in a combination with the lowest IL-2 is marked, that has defined pronounced imbalance of interleukin production. For a moment of the most traumatic manipulations on the background of ropivacain application decrease in synthesis of proinflammatory IL-1β and strengthening of immunoregulatory IL-2 secretion were observed. Ropivacain provides immunopreserving influence.
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For citations:
Zharnikov A.V. Influence of local anesthetics on dynamics of IL-1 β and IL-2 content in persons of elderly and senile age in the conditions of the prolonged spinal anesthesia. Yakut Medical Journal. 2011;(3):26-29.
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