Ratio of immunocompetent cells and NLR index in men of extreme professions (hydrographers) in the Arctic region of the Russian Federation
https://doi.org/10.25789/YMJ.2024.88.20
Abstract
A study was conducted to assess the ratio of lymphocyte phenotypes CD10, CD71, CD95 and the NLR index in men working on rotating shifts in the Arctic. The obtained data on the median ratio of the lymphoproliferation process (CD10) to the lymphapoptosis process (CD95) in hydrographers allow us to state that they have a practically balanced immune status regardless of the length of their shift, and the neutrophil to lymphocyte ratio (NLR) remains within optimal normal limits, in contrast to permanent residents of the Arctic region. It has been established that the ratio of lymphocyte levels with the CD71/CD95 marker, regardless of the length of the shift or residence in the Arctic region, is an indicator of sustainable adaptation and can serve as an assessment of the adaptability of the immune system in Arctic conditions. It was determined that the duration of the shift in the investigated hydrographers was associated exclusively with fluctuations in the NLR median and the ratio of CD10/95 cell concentrations. It should be assumed that shift workers have a more dynamic adaptive immunity, which facilitates their capacity to rapidly regenerate immune functions and, possibly, shortens the duration of immune response of a healthy person in extreme conditions.
About the Authors
M. S. Kabbani
ФИЦ комплексного изучения Арктики им. акад. Н.П. Лаверова УрО РАН
Russian Federation
Russian Federation
L. S. Shchegoleva
ФИЦ комплексного изучения Арктики им. акад. Н.П. Лаверова УрО РАН
Russian Federation
Russian Federation
E. Yu. Shashkova
ФИЦ комплексного изучения Арктики им. акад. Н.П. Лаверова УрО РАН
Russian Federation
Russian Federation
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Review
For citations:
Kabbani M.S., Shchegoleva L.S., Shashkova E.Yu. Ratio of immunocompetent cells and NLR index in men of extreme professions (hydrographers) in the Arctic region of the Russian Federation. Yakut Medical Journal. 2024;(4):84-87. (In Russ.) https://doi.org/10.25789/YMJ.2024.88.20
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