Study of angiotensin converting enzyme (ACE I/D) gene and cholesterol ester transfer protein (СЕТР D442G) gene polymorphism in elderly patients with coronary heart disease living in Yakutia
Abstract
The authors have studied I/D polymorphism of ACE gene and CETP D442G gene in group of senior patients with coronary heart disease in regard to nationality, age, sex and coronary heart disease clinical manifestations. Having analyzed ACE I/D gene polymorphism the authors found out the association of genotype II with old myocardial infarction (OMI) (Q-negative), left ventricle hypertrophy (LVH) ( with Sokolov-Lyon sign), sick sinus syndrome (SSS) and with a high angina functional class (AFC).
About the Authors
N. S. Arkhipova
YSC CMP RAMS
Россия
Россия
Arkhipova Natalia Spartakovna – junior research associate
doctor-cardiologist
E. K. Popova
North-East Federal University
Россия
Россия
Popova Elena Kapitonovna – candidate of medical sciences, associate professor of Propaedeutic and Faculty Therapy
L. V. Grigoriev
YSC CMP RAMS
Россия
Россия
Grigoriev Lena Valerevna – candidate of medical sciences, laboratory chief
A. L. Ar’ev
St.Petersburg Medical Academy of Post-graduating Study
Россия
Россия
Ar’ev Alexander Leonidovich – Doctor of Medicine, professor of Gerentology and Geriatrics
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Review
For citations:
Arkhipova N.S., Popova E.K., Grigoriev L.V., Ar’ev A.L. Study of angiotensin converting enzyme (ACE I/D) gene and cholesterol ester transfer protein (СЕТР D442G) gene polymorphism in elderly patients with coronary heart disease living in Yakutia. Yakut Medical Journal. 2011;(1):40-42.
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