Proadrenomedullin as a biomarker of COVID -19 poor outcome: a meta-analysis and systemic review
https://doi.org/10.25789/YMJ.2023.82.23
Abstract
The aim of this study was to analyse and summarise all researches about proadrenomedullin (pro-ADM) prognostic value as covid-19 severity and mortality early predictor in patients with novel coronavirus infection (NCVI) COVID-19.
After a literature search and selection, we found 19 articles eligible to inclusion in a meta-analysis. We found pro-ADM had significantly high values in patients both admitted to the general department and ICU-patients with unfavourable outcomes. Determining the level of pro-ADM is optimal at the early stages of inpatient treatment, starting from the emergency department, for stratifying patients according to the severity, making a decision on hospitalization and a differential treatment approach.
About the Authors
N. A. Chulakova
Medical Institute of the North-Eastern Federal District. M.K. Ammosov University
Russian Federation
Russian Federation
Faculty of Postgraduate Medical Education
Yakutsk
A. F. Potapov
Medical Institute of the North-Eastern Federal District. M.K. Ammosov University
Russian Federation
Russian Federation
Faculty of Postgraduate Medical Education
Yakutsk
A. A. Ivanova
Medical Institute of the North-Eastern Federal District. M.K. Ammosov University
Russian Federation
Russian Federation
Faculty of Postgraduate Medical Education
Yakutsk
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Review
For citations:
Chulakova N.A., Potapov A.F., Ivanova A.A. Proadrenomedullin as a biomarker of COVID -19 poor outcome: a meta-analysis and systemic review. Yakut Medical Journal. 2023;(2):96-102. https://doi.org/10.25789/YMJ.2023.82.23
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