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Molecular - genetic typing and study of resistance to antibiotics of nosocomial P. Aeruginosa in a multiprofile hospital

Abstract

The article presents the results of molecular genetic typing and studying of resistance to antibiotics of Pseudomonas aeruginosa nosocomial strains, isolated from the clinical samples of the patients in period of 2010-2011. Clonal spread of multidrug-resistant (XDR) metal-beta-lactamaseproducing P.aeruginosa strains ST235 (VIM-2) were revealed.

About the Authors

S. H. Shamayeva
ГБУ РС(Я) «РБ№2-ЦЭМП»
Russian Federation


E. U. Skleenova
НИИ антимикробной химиотерапии ГБОУ ВПО «Смоленская государственная медицинская академия» МЗ и СР РФ
Russian Federation


M. V. Eidelstein
НИИ антимикробной химиотерапии ГБОУ ВПО «Смоленская государственная медицинская академия» МЗ и СР РФ
Russian Federation


V. N. Markova
ГБУ РС(Я) «РБ№2-ЦЭМП»
Russian Federation


N. N. Sveshnikova
ГБУ РС(Я) «РБ№2-ЦЭМП»
Russian Federation


K. M. Petrova
ГБУ РС(Я) «РБ№2-ЦЭМП»
Russian Federation


A. F. Potapov
СВФУ им. М.К. Аммосова
Russian Federation


U. S. Portnyagina
ИПОВ СВФУ; ГБУ РС(Я) «РБ№2-ЦЭМП»
Russian Federation


A. S. Matveev
ГБУ РС(Я) «РБ№2-ЦЭМП»
Russian Federation


T. S. Makarova
ГБУ РС(Я) «РБ№2-ЦЭМП»
Russian Federation


N. M. Gogolev
СВФУ им. М.К. Аммосова
Russian Federation


A. A. Kuzmina
СВФУ им. М.К. Аммосова
Russian Federation


N. A. Varfolomeeva
СВФУ им. М.К. Аммосова
Russian Federation


I. Sh. Malogulova
СВФУ им. М.К. Аммосова
Russian Federation


References

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2. Non-fermentative gram-negative pathogens of nosocomial infections in resuscitation and intensive care units in Russia: problem of antibiotic resistance / G.K. Reshedko, E.L. Ryabkova, A.N. Faras-chuk [et al.] // Clin Microbiol Antimicrob Chemother. – 2006. – 8 (3). – P. 243-259.

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4. M.V. Edelstein. Methods of detection of metal-beta-lactamases in Gram-negative nonfermenting bacteria / M.V. Edelstein // Methods of clinical laboratory tests. - M.: Laboratory, 2009. – V.3. – P. 404-411.

5. Bergey's Manual of Determinative Bacteriology. – Baltimore: Williams and Wilkins, 1994.

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8. Primary mechanisms mediating aminoglycoside resistance in the multidrug resistant Pseudomonas aeruginosa clinical isolate PA7 / Q. Samuelsen [et al.] // Microbiology. – 2010.


Review

For citations:


Shamayeva S.H., Skleenova E.U., Eidelstein M.V., Markova V.N., Sveshnikova N.N., Petrova K.M., Potapov A.F., Portnyagina U.S., Matveev A.S., Makarova T.S., Gogolev N.M., Kuzmina A.A., Varfolomeeva N.A., Malogulova I.Sh. Molecular - genetic typing and study of resistance to antibiotics of nosocomial P. Aeruginosa in a multiprofile hospital. Yakut Medical Journal. 2012;(3):16-18.

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)