Medico-geographical analysis of frequent congenital malformations in newborns in the period from 2007 to 2020 in the Republic of Sakha (Yakutia)
https://doi.org/10.25789/YMJ.2023.82.19
Abstract
The article presents the results of the analysis of data from 13-year monitoring of congenital malformations (CM) in the Republic of Sakha (Yakutia) according to the Republican Genetic Register of Hereditary and Congenital Pathology of the Medical and Genetic Center of the SAI RH # 1 – NCM. The results of the application of the cartographic method in the analysis of the frequency of CM showed the geographical unevenness of its distribution on the territory of Yakutia. During the period of long-term monitoring, the highest frequency of CM was recorded in the Arctic regions of the Republic.
Supporting agencies: The work was supported by the State Assignment of the Ministry of Science and Higher Education of the Russian Federation (project № FSRG-2020-0014 "Genomics Arctic Regions: epidemiology, heredity and pathology")
About the Authors
A. I. Fedorov
MI NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Yakutsk
A. L. Sukhomyasova
MGTS RB No. 1-NCM; MI NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Yakutsk
A. L. Danilova
MI NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Yakutsk
A. N. Sleptsov
Medical and Genetic Center of the Republic of Belarus No. 1-NCM; MI NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Yakutsk
V. V. Filippova
EN NEFU named after M.K. Ammosov; IGIiPMNS SB RAS
Russian Federation
Russian Federation
Yakutsk
N. R. Maksimova
MI NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Yakutsk
References
1. Demikova N.S. Epidemiological monitoring of congenital malformations in the Russian Federation and its importance in the prevention of congenital anomalies in children : Dissertation of the Doctor of the Medical Sciences: 14.00.09: defended in 2005 / Demikova Natalia Sergeevna. M., 2005.
2. Demikova N.S., Lapina A.S. Congenital malformations in the regions of the Russian Federation (monitoring results for 2000-2010) // Russian Bulletin of Perinatology and Pediatrics. 2012. No. 2. 91-98 pp.
3. Malkhazova S.M. Medical-geographical Analysis of the Territory: Mapping, Assessment, Forecast / S.M. Malkhazova. M.: Scientific world, 2001. p. 240
4. Minaycheva L.I. Genetic and Epidemiological Study of Congenital Malformations in Siberian Populations: Monitoring, Medical Genetic Counseling, Clinical Examination : Dissertation of the Doctor of the Medical Sciences: 03.02.07: defended in 2014 / Minaycheva Larisa Ivanovna. Tomsk, 2014
5. Ponomareva G.A., Okhlopkov M.N. Problems of Spatial and Socio-Economic Development of the Uluses of the Arctic Zone of the Republic of Sakha (Yakutia) // National Interests: Priorities and Security. 2013. No. 47 (236). 20-25 pp.
6. Government of the Republic of Sakha (Yakutia). Strategy for the Socio-Economic Development of the Republic of Sakha (Yakutia) until 2030 with the Definition of a Target Vision until 2050 [Text]. Yakutsk, 2016. P. 332
7. Puzyrev V.P., Tomsky M.I. Genetic studies of the population of Yakutia. Yakutsk: YSC CMP SB RAMS, 2014. P. 336
8. Timofeev L.F., Petrova P.G., Borisova N.V. [et al.]. Medical-geographical Situation in the Eastern and Southern Economic Zones of the Republic of Sakha (Yakutia) [Text] // Bulletin NEFU named after M.K. Ammosov. Ser. Medical Sciences. Yakutsk: NEFU Publishing House, 2018. No. 1 (10). 15-26 pp.
9. Best K.E., Rankin J., Dolk H., Loane M. Multilevel analyses of related public health indicators: The European Surveillance of Congenital Anomalies (EUROCAT) Public Health Indicators // Paediatr Perinat Epidemiol. 2020; 34:122–129. doi: 10.1111/ppe.12655
10. Finnel R.H., Caiaffa C.D., Kim S-E [et al.]. Gene Environment Interactions in the Etiology of Neural Tube Defects // Front. Genet. 2021. 12:659612. DOI: 10.3389/fgene.2021.659612
11. Loane M., Dolk H., Garne E. [et al.]. EUROCAT data quality indicators for population-based registers of congenital anomalies // Birth Defects Res. A Clin Mol Teratol. 2011. (1). Pp. 23-30. DOI: 10.1002/bdra.20779
12. National Birth Defects Prevention Network National population-based estimates for major birth defects, 2010–2014 / Mai C.T., Isenburg J.L., Canfield M.A., Meyer R.E., Correa A., Al-verson C. J., Lupo P.J., Riehle-Colarusso T., Cho S.J., Aggarwal D., Kirby R.S. // Birth Defects Res. 2019 November 01. 111(18): Pp. 1420–1435. doi: 10.1002/bdr2.1589
13. Risk Assessment for Birth Defects in Offspring of Chinese Pregnant Women / Qu P, Zhao D, Yan M, Liu D, Pei L, Zeng L, Yan H, Dang S. In t J Environ Res Public Health. 2022 Jul 14; 19(14): 8584. doi: 10.3390/ijerph19148584
14. The International Clearinghouse for Birth Defects Surveillance and Research http://www.icbdsr.org [electronic resource]
Review
For citations:
Fedorov A.I., Sukhomyasova A.L., Danilova A.L., Sleptsov A.N., Filippova V.V., Maksimova N.R. Medico-geographical analysis of frequent congenital malformations in newborns in the period from 2007 to 2020 in the Republic of Sakha (Yakutia). Yakut Medical Journal. 2023;(2):77-80. https://doi.org/10.25789/YMJ.2023.82.19
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