Change of anti-inflammatory cytokines concentration in patients with parainfluenza
Abstract
The aim was to determine the concentration of anti-inflammatory cytokines (IL-1Ra, IL-4 and IL-10) in the serum of patients with parainfluenza. We examined 19 patients with moderate parainfluenza aged 15-54 years who have the disease run a positive, without complications. Blood were taken during the acute period of disease and reconvalescent. Served as control blood of healthy donors (n = 18). Defined increase in all investigated cytokines in the acute period of disease and during convalescence. We set the activation level of anti-inflammatory “cytokine network” throughout the disease, indirectly indicating the high activity of effector cells of blood, synthesizing data cytokines. The results were used to create an expert system “Quick diagnosis and prognosis of ARVI”.
About the Author
M. V. Shipilov
"Clinical Hospital № 1" in Smolensk
Россия
Россия
Mikhail Vasilevich Shipilov, candidate of medical science Smolenskmedinvest" (Smolensk), doctor-expert
head of infectious department № 2, phone: 8(951)6944168 Address: 214031, Smolensk, Prospect Builders, 14-B, Apt. 11
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For citations:
Shipilov M.V. Change of anti-inflammatory cytokines concentration in patients with parainfluenza. Yakut Medical Journal. 2012;(1):8-10.
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