Evaluation of the effect of some biological properties of sprout juice of Yakut wheat varieties on women’s bodies
https://doi.org/10.25789/YMJ.2025.91.10
Abstract
The article presents a study on the effectiveness of the immunomodulatory and anti-inflammatory properties of juice from wheat sprouts growing in the extreme climatic conditions of the Far North. Based on clinical and immunological analyses of 27 volunteers from Sakha women aged 40 to 60 years who took whitegrass for 24 days in a volume of 20 ml, positive changes were obtained: there is a significant increase in lymphocytes and monocytes, which indicates the activation of immune mechanisms while maintaining homeostasis. In 29,6% of the participants, elevated ESR levels returned to normal after taking the juice, which shows the anti-inflammatory effect of witgrass. Restoration of leukocyte and granulocyte levels in 14.8% of participants with reduced levels indicates support for hematopoiesis and immunological balance. A moderate increase in IgA, IgM, and IgG antibodies after juice intake causes a strengthening of humoral immunity and the interaction of various parts of the defense system. The results obtained are consistent with the literature data and open up opportunities for further study of the biological properties of juice from the sprouts of local wheat varieties growing in the extreme climatic conditions of Yakutia, its potential for use in complex therapy of immune disorders and for the development of effective natural remedies for the treatment and prevention of many diseases in the North.
About the Authors
L. D. Olesova
ФГБНУ «Якутский научный центр комплексных медицинских проблем»
Russian Federation
Russian Federation
N. T. Borisova
ФГБНУ «Якутский научный центр комплексных медицинских проблем»
Russian Federation
Russian Federation
E. D. Okhlopkova
ФГБНУ «Якутский научный центр комплексных медицинских проблем»
Russian Federation
Russian Federation
S. D. Efremova
ФГБНУ «Якутский научный центр комплексных медицинских проблем»
Russian Federation
Russian Federation
References
1. Zverev Ya.F. Flavonoids through the eyes of a pharmacologist. Antioxidant and anti-inflammatory activity // Reviews on Clinical Pharmacology and Drug Therapy. 2017; 5(4): 5-13. doi: 10.17816/RCF1545-13.
2. History of Wittgrass research URL: https://vc.ru/u/1059694-ekoferma-babiesgreen/351403-chto-takoe-vitgrass-i-sok-iz-vitgrassa (date of request: 03/01/2025).
3. K. Murphy. Immunobiology according to Janway / book Murphy, K. N. Weaver; translated from English; edited by N. G. Ignatieva, O. N.A. N. Svitich, I. N.N. Dyakov. M. N.: Logosphere, 2020; 1184.
4. Microgreens. Witgrass cultivation / M.V.Anosova, V.I. Manzhesov, T.N.Tertychnaya, [et al.] // Technologies and commodity science of agricultural products. 2021; 16(1): 63-70.
5. Olesova L.D. The prospects of a biogenic product from wheat germ in the prevention and treatment of diseases in the North // Medicine. Sociology. Philosophy. 2021. 2:20-24 doi: 10.24411/2686-9365-2021-00002
6. Features of immunological reactivity in Sami women / A.V. Samodova, L.K. Dobrodeeva, S.N. Balashova, K.O. [et al.] // Human Ecology. 2022; 29(9):673–683. DOI: https://doi.org/10.17816/humeco105563.
7. Pashinskaya K.O., Samodova A.V., Dobrodeeva L.K. Transport functions of immunoglobulins in the inhabitants of the European territory of the Arctic of the Russian Federation / News of the Russian Academy of Sciences. The series is biological. 2023; 5: 537-545. doi: 10.31857/S1026347022600364.
8. Petrova P.G. Ecological and physiological aspects of human adaptation to the conditions of the North. Vestnik of North-Eastern Federal University. Medical Sciences. 2019; 2 (15): 29-38.
9. Perfection of technology of production of bakery products on the basis of crushed sprouted wheat grain / F.K. Huzin, Z.A. Kanarkaya, А.R. Ivleva, [et. al.] // Proceedings of VSUET. 2017; Vol. 79. No 1: 178–187. doi:10.20914/2310-1202-2017-1-178-187.
10. Chaim Hershko. Assessment of iron deficiency // Haematologica.Vol. 103 No. 12 (2018): December, 2018. doi: 10.3324/haematol.2018.205575.
11. Herman K.E., Tuttle K.L. Overview of secondary immunodeficiency // Allergy Asthma Proc. 2024 Sep. 1; 45(5):347-354. doi: 10.2500/aap.2024.45.240063. PMID: 39294908.
12. Myachikova N.I., Sorokopudov V.N., Binkovskaya O.V., Dumacheva E.V. Germinated seeds as a source of food and biologically active substances for the human body // Balanced diet, nutritional supplements and biostimulants. 2014; 2: 28-29.
13. Naureen, Z., Dhuli, K., Donato, K., Aquilanti, B., Velluti, V., Matera, G., et al. (2022). Foods of the Mediterranean diet: Tomato, olives, chili pepper, wheat flour and wheat germ // J. Prev. Med. Hyg. 6363, E4–E11. doi: 10.15167/2421-4248/jpmh2022.63.2S3.2740.
14. Netea M.G., Joosten L.A., Latz E., Mills K.H., Natoli G., Stunnenberg H.G., O'Neill L.A., Xavier R.J. Trained immunity: A program of innate immune memory in health and disease / Science. 2016 Apr 22;352(6284):aaf1098. doi: 10.1126/science.aaf1098. Epub 2016 Apr 21. PMID: 27102489; PMCID: PMC5087274.
15. Salehi M., Rashidinejad A. Multifaceted roles of plant-derived bioactive polysaccharides: A review of their biological functions, delivery, bioavailability, and applications within the food and pharmaceutical sectors // Int J Biol Macromol. 2025 Feb;290:138855. doi: 10.1016/j.ijbiomac.2024.138855. Epub 2024 Dec 17. PMID: 39701227.
16. Seyidoglu N., Aydin C. (2024). Insight of the Recent Perspectives from Psychoneuroimmunology: Stress, Nutrition and Life Quality. In: Rezaei, N., Yazdanpanah, N. (eds) // PsychoNeuroImmunology. Integrated Science, vol 30. Springer, Cham. https://doi.org/10.1007/978-3031-73061-0_9.
17. Shakoor, H., Feehan, J., Apostolopoulos, V., Platat, C., Al Dhaheri, A.S., Ali, H.I., Ismail, L.C., Bosevski, M., Stojanovska, L. Immunomodulatory Effects of Dietary Polyphenols // Nutrients 2021, 13, 728. https://doi.org/10.3390/nu13030728
18. Yu J, Bi X, Yu B, Chen D. Isoflavones: Anti-Inflammatory Benefit and Possible Caveats // Nutrients. 2016 Jun 10;8(6):361. doi: 10.3390/nu8060361. PMID: 27294954; PMCID: PMC4924202.
Review
For citations:
Olesova L.D., Borisova N.T., Okhlopkova E.D., Efremova S.D. Evaluation of the effect of some biological properties of sprout juice of Yakut wheat varieties on women’s bodies. Yakut Medical Journal. 2025;(3):43-47. https://doi.org/10.25789/YMJ.2025.91.10
Views:
118
Email this article 