Determination of biochemical markers of altered hepatic metabolism in white rats exposed to X-rays
R. J. Karimova,
Sh. M. Polukhova,
M. B. Zulfugarova,
F. E. Gulieva,
A. F. Rustamova,
E. M. Musayeva,
Z. G. Aliyeva,
A. V. Aslanova,
N. A. Panakhova https://doi.org/10.25789/YMJ.2025.91.06
Abstract
The article presents information about a study conducted to study changes in the level of enzymes and free products of lipid peroxidation in metabolic disorders in the liver of experimental animals exposed to X-ray radiation. The study was conducted on 42 intact white rats, which were divided into three groups. The first group (control) included 6 white rats. The second group included 18 intact white rats exposed to X-rays. In the third group, 10 days after the cessation of X-ray irradiation (18 animals), the level of liver enzymes in the blood was measured. Levels of lipid peroxidation (POL), malondialdehyde (MDA), diene conjugates (DC), hydrogen peroxide (H2O2), creatine phosphokinase (CK), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), gamma-glutamyltransferase (GGT), aspartate aminotransferase (AST) were determined in the blood of experimental animals and alanine aminotransferase (ALT).
About the Authors
R. J. Karimova
Азербайджанский медицинский университет
Azerbaijan
Azerbaijan
Sh. M. Polukhova
Азербайджанский медицинский университет
Azerbaijan
Azerbaijan
M. B. Zulfugarova
Азербайджанский медицинский университет
Russian Federation
Russian Federation
F. E. Gulieva
Азербайджанский медицинский университет
Azerbaijan
Azerbaijan
A. F. Rustamova
Азербайджанский медицинский университет
Azerbaijan
Azerbaijan
E. M. Musayeva
Азербайджанский медицинский университет
Russian Federation
Russian Federation
Z. G. Aliyeva
Азербайджанский медицинский университет
Russian Federation
Russian Federation
A. V. Aslanova
Азербайджанский медицинский университет
Russian Federation
Russian Federation
N. A. Panakhova
Азербайджанский медицинский университет
Russian Federation
Russian Federation
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Review
For citations:
Karimova R.J., Polukhova Sh.M., Zulfugarova M.B., Gulieva F.E., Rustamova A.F., Musayeva E.M., Aliyeva Z.G., Aslanova A.V., Panakhova N.A. Determination of biochemical markers of altered hepatic metabolism in white rats exposed to X-rays. Yakut Medical Journal. 2025;(3):28-31. https://doi.org/10.25789/YMJ.2025.91.06
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