Analysis of the clinical outcomes of some gastroduodenal diseases in Yakutia: iceA1 strains of Helicobacter pylori relations with the early onset of chronic gastritis
Abstract
The article presents the results of a study of clinical outcomes in patients with several gastroduodenal diseases, depending on the allelic variants of the gene iceA Helicobacter pylori. The iceA1 strains were identified in 65,2% cases and iceA2 – in 34,7% cases. We found no associations according to gender of patients, their place of birth or residence. However, statistically significant differences in the distribution of iceA gene alleles were found depending on age of patients with chronic gastritis. Obtained results may indicate the early onset of chronic gastritis on carriers of iceA1 strains circulating in Yakutia.
Keywords
Supporting agencies: The work was supported by the project of the Ministry of Education and Science of the Russian Federation Civil Code №6.656.2014 / K, with the financial support of the grant "Scientific and Educational Foundation for Support of Young Scientists of the Republic of Sakha (Yakutia)" 201 502 010 121, and with the support of the grant of the Head of the Republic of Sakha (Yakutia), the young scientists, specialists and students (number 105‐RH February 8, 2016).
About the Authors
N. N. Gotovtsev
ЯНЦ КМП
Russian Federation
Russian Federation
N. A. Barashkov
ЯНЦ КМП
Russian Federation
Russian Federation
K. E. Savvinova
СВФУ им. М.К. Аммосова
Russian Federation
Russian Federation
M. V. Pak
СВФУ им. М.К. Аммосова
Russian Federation
Russian Federation
M. P. Alexeeva
РБ№1-НЦМ
Russian Federation
Russian Federation
K. S. Loskutova
РБ №1-НЦМ
Russian Federation
Russian Federation
V. G. Pshennikova
ЯНЦ КМП
Russian Federation
Russian Federation
A. M. Rafailov
СВФУ им. М.К. Аммосова
Russian Federation
Russian Federation
S. N. Lekhanova
СВФУ им. М.К. Аммосова
Russian Federation
Russian Federation
E. Crubézy
Университет Версаль-Сен-Кантен-ан-Ивелин
France
France
S. A. Fedorova
СВФУ им. М.К. Аммосова
Russian Federation
Russian Federation
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Review
For citations:
Gotovtsev N.N., Barashkov N.A., Savvinova K.E., Pak M.V., Alexeeva M.P., Loskutova K.S., Pshennikova V.G., Rafailov A.M., Lekhanova S.N., Crubézy E., Fedorova S.A. Analysis of the clinical outcomes of some gastroduodenal diseases in Yakutia: iceA1 strains of Helicobacter pylori relations with the early onset of chronic gastritis. Yakut Medical Journal. 2016;(3):14-17.
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