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Cases of adrenocortical cancer in children in the Republic of Sakha (Yakutia)

https://doi.org/10.25789/YMJ.2022.79.29

Abstract

The article describes cases of primary tumor of the adrenal cortex and adrenocortical cancer in two children. In one case, the tumor turned out to be hormone-active, with increased cortisol secretion with the development of Icengo-Cushing syndrome. In the first case, stage II of the tumor process was established, in the second – stage IV. The children received combined treatment, surgery and chemotherapy. In the first patient, the treatment was successful, the child is in remission for 4 years, in the second case, the outcome is fatal, due to the progression of the malignant process.

About the Authors

E. F. Argunova
Medical Institute, M.K. Ammosov NEFU
Russian Federation

Argunova Elena Filippovna – PhD, Associate Professor



S. A. Nikolaeva
Pediatric Center No. 1-National Centre of Medicine
Russian Federation

Nikolaeva Sargylana Afanasyevna – pediatric oncologist of the oncological department 



E. M. Kharabaeva
Pediatric Center No. 1-National Centre of Medicine
Russian Federation

Kharabayeva Elena M. – Head of the Oncology Department



S. A. Kondratieva
Pediatric Center No. 1-National Centre of Medicine
Russian Federation

Kondratieva Sargylana Afanasyevna – pediatric oncologist of the Oncology Department



V. B. Egorova
Medical Institute, M.K. Ammosov NEFU
Russian Federation

Burtseva Tatiana Egorovna – MD, Professor 



O. N. Ivanova
Medical Institute, M.K. Ammosov NEFU
Russian Federation

Ivanova Olga Nikolaevna – MD, Professor 



A. A. Munhalov
Medical Institute, M.K. Ammosov NEFU
Russian Federation

Munkhalov Alexey Andreevich – student IFPRS, Department of English Philology



T. A. Argunova
Medical Institute, M.K. Ammosov NEFU
Russian Federation

Argunova Tamara Alexandrovna – 6th year student, Pediatric Department,



References

1. Results of surgical treatment of localized and locally advanced adrenocortical cancer in children / A.S. Dark, A.P. Kazantsev, P.A. Kerimov [et al.] // Russian Journal of Pediatric Hematology and Oncology. - 2021. - V. 2, No. 8. - P. 42–9.

2. The role of surgical treatment in stage IV adrenocortical cancer / A.S. Dark, A.P. Kazantsev, P.A. Kerimov [et al.] // Ibid. – V. 4, No. 8. – P. 31–8.

3. Sharoev T.A. Cancer of the adrenal cortex in children / T. A. Sharoev, N. M. Ivanova, S. B. Bondarenko // Oncopediatrics. - 2015. - T. 2, No. 1. - P. 16-25.

4. Behrman R.E., Kliegman R., Jenson H.B. Adrenocortical Tumors. Nelson Textbook of Pediatrics, 20th Edition. Philadelphia WB Saunders; 2015; 2726-2727.

5. Charles G. D. Brook, Peter E. Clayton, Rosalind S. Brown. Endocrine neoplasia in childhood. Brook's Clinical Pediatric Endocrinology, 6th Edition, UK, WileyBlackwell; 2009; 428-432.


Review

For citations:


Argunova E.F., Nikolaeva S.A., Kharabaeva E.M., Kondratieva S.A., Egorova V.B., Ivanova O.N., Munhalov A.A., Argunova T.A. Cases of adrenocortical cancer in children in the Republic of Sakha (Yakutia). Yakut Medical Journal. 2022;(3):115-118. https://doi.org/10.25789/YMJ.2022.79.29

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)