Molecular epidemiology of hepatitis B virus in Yakutia
Abstract
Heterogeneity of hepatitis B virus and its link with clinical course of infection and its outcomes remains one of priority directions of researches in Republic Sakha (Yakutia), as the region with high incidence of this disease. Blood serum samples with chronic hepatitis, registered in dispensary of various regions of the Republic Sakha (Yakutia), have been investigated. On the basis of results of the research by means of molecular – biological methods in the republic a genotype D was considered as the dominating genotype at patients with CHB, and sufficiently a large number of patients are infected simultaneously by two genotypes, most intensively circulating in the territory of Republic (A, D, C). For adequate therapy of such diseases it is necessary to consider characteristics of excreted isolates.
About the Authors
V. V. Gerasimova
СВФУ им. М.К. Аммосова; ЯНц КМП СО РАМН
Russian Federation
Russian Federation
N. R. Maksimova
СВФУ им. М.К. Аммосова; ЯНц КМП СО РАМН
Russian Federation
Russian Federation
I. A. Levakova
ФбУН Санкт-Петербургский НИИ эпидемиологии и микробиологии им. Пастера
Russian Federation
Russian Federation
S. L. Mukomolov
ФбУН Санкт-Петербургский НИИ эпидемиологии и микробиологии им. Пастера
Russian Federation
Russian Federation
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Review
For citations:
Gerasimova V.V., Maksimova N.R., Levakova I.A., Mukomolov S.L. Molecular epidemiology of hepatitis B virus in Yakutia. Yakut Medical Journal. 2014;(3):54-57.
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