Morphological features of kidneys at rats’ posterity affected by chronic pre-natal, acute post-natal and mixed hypoxia
Abstract
In this experimental study macroscopic and microscopic features of kidneys of fetuses and neonates affected by chronic fetal (CFH), acute postnatal (APH) and mixed hypoxia (MH) are established. The authors have shown that CFH and MH result in reduction of kidney weight in fetuses and newborns, and APH does not affect the weight of the newborn kidney. In kidneys of fetuses and newborns there were signs of immaturity, degenerative, necrotic, inflammatory, sclerotic changes, hemodynamic disturbances and signs of edema, they mostly marked in modeling MH and CFH and moderately marked in modeling APH. The identified structural changes in the kidneys of fetuses and neonates affected by different types of hypoxia can lead to the development of nephrologic pathology in these children in the future ontogenesis.
About the Authors
V. D. Markovsky
Харьковский национальный медицинский университет
Ukraine
Ukraine
I. V. Sorokina
Харьковский национальный медицинский университет
Ukraine
Ukraine
M. S. Miroshnichenko
Харьковский национальный медицинский университет
Ukraine
Ukraine
A. A. Adeyemi
Харьковский национальный медицинский университет
Ukraine
Ukraine
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Review
For citations:
Markovsky V.D., Sorokina I.V., Miroshnichenko M.S., Adeyemi A.A. Morphological features of kidneys at rats’ posterity affected by chronic pre-natal, acute post-natal and mixed hypoxia. Yakut Medical Journal. 2015;(2):94-97. (In Russ.)
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