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Features of Cytokine Status of Pregnant Women with Chronic Pyelonephritis, Depending on the Placenta Morphological Characteristics

Abstract

It has been shown that for an objective appraisal of the impact of active influence of chronic pyelonephritis on the feto‐placental complex is possible in determining the constituents of pro‐ and anti‐inflammatory cytokines. The results of this research on cytokine status give an evidence of the unstabilized nature of the immune system in women with CP. In spite of the complete clinical and laboratory remission of the disease, contributions to the development of gestational complications were due to the lack of pregravidal training and early prevention of placental insufficiency. It has been established that, despite the absence of specific features in the placenta of women with chronic pyelonephritis that highlighted to the compensatory and sub‐compensatory changes against the backdrop of dystrophic, microcirculatory and other disorders, reflecting not only the provision of the required conditions for the existence of the fetus, but as well as the degree of destructive lesions and severe shift in immunological equilibrium.

About the Authors

B. M. Gasanova
Dagestan State Medical Academy
Russian Federation

Gasanova Bahu Musalaevna – МD., Assistant of Department of Obstetrics and Gynecology

Makhahkala, Republic of Dagestan; 367000, Lenin Square 1



N. I. Duglas
M.K.Ammosov North‐Eastern Federal University
Russian Federation

Duglas Natalia Ivanovna ‐ obstetrician‐gynecologist, MD, Head of the Department of Obstetrics and Gynecology Faculty of Postgraduate Training for Doctors, Medical Institute 



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Review

For citations:


Gasanova B.M., Duglas N.I. Features of Cytokine Status of Pregnant Women with Chronic Pyelonephritis, Depending on the Placenta Morphological Characteristics. Yakut Medical Journal. 2015;(4):14-16.

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)