Some features of restructuring cerebral microvessels at diabetes
Abstract
To identify specificity of microvascular damage of the brain and a degree of structural abnormalities of vessel walls in diabetes (D) types 1 and 2 the morphological, morphometric and immunohistochemical research of autopsy cerebellum of patients with diabetes mellitus has been conducted. The structural change of brain microvessels in diabetes is noted to be a long-term process and characterized by low levels of expression of proliferation markers and apoptosis in fibrosis and hyalinosis according to the immunohistochemical study. The staging of microvascular damage of the brain in DM is defined, 3 morphological stages are allocated.
About the Author
Yu. N. AvramenkoUkraine
Julia N. Avramenko– teasching assistant of the Zaporojskiy State Medical University.
References
1. Balabolkin M.I. Diabetology / M.I. Bala-bolkin. – M.: Medicine, 2000. – P. 672.
2. Balabolkin M.I. Medical application of Milgamma in complex therapy of diabetic neuropathy: Methodic recommendations / M.I. Balabolkin. – M., 2002.
3. Melchinskaya E.N. The main ap-proaches to treatment of microvascular complications of diabetes [Electron resource] / E.N. Melchinskaya // MEDI.RU Diabetology. – 2011. – №1. – Access http://medi.ru/doc/170512.htm (date accessed 28/08/2015).
4. Kotov S.V. Diabetic polyneuropathy / S.V. Kotov, A.P. Kalinin, I.G. Rudakov. – M.: Medicine, 2002. – P. 440.
5. Petrov S.V. Guidance on the immunohistochemical diagnosis of human tumors / S.V. Petrov, N.T. Reichlin. – Kazan: Titul, 2004. – P. 451
Review
For citations:
Avramenko Yu.N. Some features of restructuring cerebral microvessels at diabetes. Yakut Medical Journal. 2015;(2):70-72.
                    
        







